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Genomics, Intellectual Disability, and Autism
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Journal Article
Genomics, Intellectual Disability, and Autism
2012
Overview
The authors discuss the substantive impact of recent advances in genomic technologies on the diagnosis and understanding of intellectual disability and autism.
Intellectual disability, which is characterized by significant limitations in both intellectual functioning and adaptive behavior that begin before the age of 18 years,
1
affects 1.5 to 2% of the population in Western countries.
2
A diagnosis of intellectual disability is usually made when IQ testing reveals an IQ of less than 70, which means that often the diagnosis is not made until late childhood or early adulthood. However, most persons with intellectual disability are identified early in childhood on the basis of concern about developmental delays, which may include motor, cognitive, and speech delays. A genetic underpinning of this disorder has . . .
Publisher
Massachusetts Medical Society
Subject
Adult and adolescent clinical studies
/ Autism
/ Behavior
/ Biological and medical sciences
/ Child
/ Child Development Disorders, Pervasive - genetics
/ Genomes
/ Genomics
/ High-Throughput Nucleotide Sequencing
/ Humans
/ Intellectual Disability - diagnosis
/ Intellectual Disability - genetics
/ Mutation
/ Polymorphism, Single Nucleotide
