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Vitreomacular interface abnormalities in the Ghanaian African
by
Hubbard, William C.
, Amoaku, Winfried M.
, Lartey, Seth
, Bernstein, Paul S.
, Pappas, Christian M.
, Virgili, Gianni
, Akafo, Stephen
, Amissah-Arthur, Kwesi N.
, Hageman, Courtney N.
, Silvestri, Vittorio
, Cushley, Laura
, Hageman, Gregory S.
, Silvestri, Giuliana
, Vitale, Albert
, Roberts, Megan
in
13
/ 14/5
/ 59
/ 692/699/3161/3175
/ 692/699/3161/3179
/ Adult
/ Age
/ Cross-Sectional Studies
/ Eye Diseases
/ Female
/ Ghana - epidemiology
/ Humans
/ Laboratory Medicine
/ Macula Lutea
/ Macular Degeneration
/ Male
/ Medicine
/ Medicine & Public Health
/ Ophthalmology
/ Pharmaceutical Sciences/Technology
/ Photography
/ Prospective Studies
/ Retrospective Studies
/ Surgery
/ Surgical Oncology
/ Tomography, Optical Coherence - methods
/ Vitreous Body
/ Vitreous Detachment - epidemiology
2024
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Vitreomacular interface abnormalities in the Ghanaian African
by
Hubbard, William C.
, Amoaku, Winfried M.
, Lartey, Seth
, Bernstein, Paul S.
, Pappas, Christian M.
, Virgili, Gianni
, Akafo, Stephen
, Amissah-Arthur, Kwesi N.
, Hageman, Courtney N.
, Silvestri, Vittorio
, Cushley, Laura
, Hageman, Gregory S.
, Silvestri, Giuliana
, Vitale, Albert
, Roberts, Megan
in
13
/ 14/5
/ 59
/ 692/699/3161/3175
/ 692/699/3161/3179
/ Adult
/ Age
/ Cross-Sectional Studies
/ Eye Diseases
/ Female
/ Ghana - epidemiology
/ Humans
/ Laboratory Medicine
/ Macula Lutea
/ Macular Degeneration
/ Male
/ Medicine
/ Medicine & Public Health
/ Ophthalmology
/ Pharmaceutical Sciences/Technology
/ Photography
/ Prospective Studies
/ Retrospective Studies
/ Surgery
/ Surgical Oncology
/ Tomography, Optical Coherence - methods
/ Vitreous Body
/ Vitreous Detachment - epidemiology
2024
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Do you wish to request the book?
Vitreomacular interface abnormalities in the Ghanaian African
by
Hubbard, William C.
, Amoaku, Winfried M.
, Lartey, Seth
, Bernstein, Paul S.
, Pappas, Christian M.
, Virgili, Gianni
, Akafo, Stephen
, Amissah-Arthur, Kwesi N.
, Hageman, Courtney N.
, Silvestri, Vittorio
, Cushley, Laura
, Hageman, Gregory S.
, Silvestri, Giuliana
, Vitale, Albert
, Roberts, Megan
in
13
/ 14/5
/ 59
/ 692/699/3161/3175
/ 692/699/3161/3179
/ Adult
/ Age
/ Cross-Sectional Studies
/ Eye Diseases
/ Female
/ Ghana - epidemiology
/ Humans
/ Laboratory Medicine
/ Macula Lutea
/ Macular Degeneration
/ Male
/ Medicine
/ Medicine & Public Health
/ Ophthalmology
/ Pharmaceutical Sciences/Technology
/ Photography
/ Prospective Studies
/ Retrospective Studies
/ Surgery
/ Surgical Oncology
/ Tomography, Optical Coherence - methods
/ Vitreous Body
/ Vitreous Detachment - epidemiology
2024
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Vitreomacular interface abnormalities in the Ghanaian African
Journal Article
Vitreomacular interface abnormalities in the Ghanaian African
2024
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Overview
Background/Objective
Describe vitreomacular interface abnormalities (VMIA) using spectral-domain optical coherence tomography (SD-OCT), and correlations with age-related macular degeneration (AMD) grade in Ghanaian Africans.
Subjects/Methods
Prospective, cross-sectional study of adults aged ≥50 years recruited in Ghana AMD Study. Participant demographics, medical histories, ophthalmic examination, digital colour fundus photography (CFP) were obtained. High-resolution five-line raster OCT, Macular Cube 512 × 128 scans, and additional line scans in areas of clinical abnormality, were acquired. SD-OCT VMI features classified by International Vitreomacular Traction Study Group system and relationships to AMD grade were evaluated. Outcomes: VMIA prevalence, posterior vitreous detachment (PVD), vitreomacular adhesions (VMA), vitreomacular traction (VMT), epiretinal membranes (ERM), correlations with AMD grade.
Results
The full Ghana AMD cohort included 718 participants; 624 participants (1248 eyes) aged ≥50 years (range = 50–101, mean = 68.8), 68.9% female were included in this analysis. CFP with OCT scans were available for 776 eyes (397 participants); 707 (91.1%) had gradable CFP and OCT scans for both AMD and VMI grading forming the dataset for this report. PVD was absent in 504 (71.3%); partial and complete PVD occurred in 16.7% and 12.0% respectively. PVD did not increase with age (
p
= 0.720). VMIA without traction and macular holes were observed in 12.2% of eyes; 87.8% had no abnormalities. VMIA was not significantly correlated with AMD grade (
p
= 0.819).
Conclusions
This provides the first assessment of VMIA in Ghanaian Africans. VMIA are common in Africans; PVD may be less common than in Caucasians. There was no significant association of AMD grade with VMIA.
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