Asset Details
Do you wish to reserve the book?
A stable hippocampal code in freely flying bats
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
A stable hippocampal code in freely flying bats
Do you wish to request the book?
A stable hippocampal code in freely flying bats
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
A stable hippocampal code in freely flying bats
2022
Overview
Neural activity in the hippocampus is known to reflect how animals move through an environment
1
,
2
. Although navigational behaviour may show considerable stability
3
–
6
, the tuning stability of individual hippocampal neurons remains unclear
7
–
12
. Here we used wireless calcium imaging to longitudinally monitor the activity of dorsal CA1 hippocampal neurons in freely flying bats performing highly reproducible flights in a familiar environment. We find that both the participation and the spatial selectivity of most neurons remain stable over days and weeks. We also find that apparent changes in tuning can be largely attributed to variations in the flight behaviour of the bats. Finally, we show that bats navigating in the same environment under different room lighting conditions (lights on versus lights off) exhibit substantial changes in flight behaviour that can give the illusion of neuronal instability. However, when similar flight paths are compared across conditions, the stability of the hippocampal code persists. Taken together, we show that the underlying hippocampal code is highly stable over days and across contexts if behaviour is taken into account.
The hippocampal code in freely flying bats is highly stable over days and across contexts if behaviour is taken into account.
Publisher
Nature Publishing Group UK,Nature Publishing Group
