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Intensive Diabetes Therapy and Ocular Surgery in Type 1 Diabetes
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Intensive Diabetes Therapy and Ocular Surgery in Type 1 Diabetes
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Journal Article
Intensive Diabetes Therapy and Ocular Surgery in Type 1 Diabetes
2015
Overview
Retinopathy, a common microvascular complication of type 1 diabetes, can lead to vision loss. Follow-up data from two studies show that intensive therapy in patients with type 1 diabetes was associated with a substantially reduced long-term risk of ocular surgery.
Retinopathy, a common microvascular complication of type 1 diabetes, is a leading cause of vision loss worldwide.
1
In the Diabetes Control and Complications Trial (DCCT),
2
6.5 years of intensive therapy aimed at achieving glycemia as close to the nondiabetic range as safely possible, as compared with conventional therapy at the time, was associated with a 76% reduction in the onset of retinopathy and a 52% reduction in disease progression. In the subsequent long-term observational follow-up, the Epidemiology of Diabetes Interventions and Complications (EDIC) study,
3
the patients in the intensive-therapy group had a durable reduction in progression of microvascular and macrovascular . . .
Publisher
Massachusetts Medical Society
Subject
/ Adult
/ Diabetes
/ Diabetes mellitus (insulin dependent)
/ Diabetes Mellitus, Type 1 - complications
/ Diabetes Mellitus, Type 1 - drug therapy
/ Diabetic Retinopathy - surgery
/ Female
/ Glycated Hemoglobin - analysis
/ Humans
/ Hypoglycemic Agents - therapeutic use
/ Male
/ Ophthalmologic Surgical Procedures - economics
/ Ophthalmologic Surgical Procedures - statistics & numerical data
/ Retina
/ Surgery
