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Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer

by Geyer, Charles E , Pritchard, Kathleen I , Keane, Maccon M , Brufsky, Adam M , Wood, William C , Makower, Della F , Reddy, Pavan S , Berenberg, Jeffrey L , Whelan, Timothy J , Wagner, Lynne I , Ellis, Matthew J , Olson, John A , Toppmeyer, Deborah L , Abrams, Jeffrey , Hayes, Daniel F , Goggins, Timothy F , Kaklamani, Virginia G , Gray, Robert J , Paik, Soonmyung , Gomez Moreno, Henry L , Badve, Sunil S , Goetz, Matthew P , Saphner, Thomas J , Albain, Kathy S , Sparano, Joseph A , Dees, Elizabeth C , Sledge, George W , Lively, Tracy , Mayer, Ingrid A , Ravdin, Peter M

in Adjuvants / Adult / Age / Age Factors / Aged / Antineoplastic Agents, Hormonal - therapeutic use / Antineoplastic Combined Chemotherapy Protocols - therapeutic use / Breast cancer / Breast Neoplasms - drug therapy / Breast Neoplasms - genetics / Breast Neoplasms - surgery / Cancer therapies / Chemotherapy / Chemotherapy, Adjuvant / Clinical trials / Disease-Free Survival / Endocrine therapy / Epidermal growth factor / ErbB-2 protein / Female / Gene expression / Gene Expression Profiling / Humans / Invasiveness / Kaplan-Meier Estimate / Medical research / Medicine / Middle Aged / Neoplasm Invasiveness / Neoplasm Recurrence, Local - genetics / Neoplasm Recurrence, Local - prevention & control / Oncology / Patients / Population / Prospective Studies / Radiation therapy / Receptor, ErbB-2 / Receptors, Estrogen / Receptors, Progesterone / Statistical analysis / Survival / Womens health / Young Adult

2018

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Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer

2018

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Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer

2018

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Journal Article

Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer

Geyer, Charles E,

Pritchard, Kathleen I,

Keane, Maccon M,

Brufsky, Adam M,

Wood, William C,

Makower, Della F,

Reddy, Pavan S,

Berenberg, Jeffrey L,

Whelan, Timothy J,

Wagner, Lynne I,

Ellis, Matthew J,

Olson, John A,

Toppmeyer, Deborah L,

Abrams, Jeffrey,

Hayes, Daniel F,

Goggins, Timothy F,

Kaklamani, Virginia G,

Gray, Robert J,

Paik, Soonmyung,

Gomez Moreno, Henry L,

Badve, Sunil S,

Goetz, Matthew P,

Saphner, Thomas J,

Albain, Kathy S,

Sparano, Joseph A,

Dees, Elizabeth C,

Sledge, George W,

Lively, Tracy,

Mayer, Ingrid A,

Ravdin, Peter M

2018

Overview

When a genetic test was used to assess prognosis, women with midrange scores were found to have similar outcomes after adjuvant treatment with either endocrine therapy alone or chemotherapy plus endocrine therapy.

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Publisher

Massachusetts Medical Society

Subject

Adjuvants

/ Adult

/ Age

/ Age Factors

/ Aged

/ Antineoplastic Agents, Hormonal - therapeutic use

/ Antineoplastic Combined Chemotherapy Protocols - therapeutic use