Asset Details
Do you wish to reserve the book?
Self-regulation and the foraging gene (PRKG1) in humans
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Self-regulation and the foraging gene (PRKG1) in humans
Do you wish to request the book?
Self-regulation and the foraging gene (PRKG1) in humans
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Self-regulation and the foraging gene (PRKG1) in humans
2019
Overview
Foraging is a goal-directed behavior that balances the need to explore the environment for resources with the need to exploit those resources. In Drosophila melanogaster, distinct phenotypes have been observed in relation to the foraging gene (for), labeled the rover and sitter. Adult rovers explore their environs more extensively than do adult sitters. We explored whether this distinction would be conserved in humans. We made use of a distinction from regulatory mode theory between those who “get on with it,” so-called locomotors, and those who prefer to ensure they “do the right thing,” so-called assessors. In this logic, rovers and locomotors share similarities in goal pursuit, as do sitters and assessors. We showed that genetic variation in PRKG1, the human ortholog of for, is associated with preferential adoption of a specific regulatory mode. Next, participants performed a foraging task to see whether genetic differences associated with distinct regulatory modes would be associated with distinct goal pursuit patterns. Assessors tended to hug the boundary of the foraging environment, much like behaviors seen in Drosophila adult sitters. In a patchy foraging environment, assessors adopted more cautious search strategies maximizing exploitation. These results show that distinct patterns of goal pursuit are associated with particular genotypes of PRKG1, the human ortholog of for.
Publisher
National Academy of Sciences
Subject
/ Adult
/ Animals
/ Cyclic GMP-Dependent Protein Kinase Type I - genetics
/ Cyclic GMP-Dependent Protein Kinase Type I - metabolism
/ Cyclic GMP-Dependent Protein Kinases - genetics
/ Cyclic GMP-Dependent Protein Kinases - metabolism
/ Drosophila Proteins - genetics
/ Drosophila Proteins - metabolism
/ Female
/ Genetics
/ Humans
/ Insects
/ Male
