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THE EFFECT OF HOOKWORM INFECTION AND URINARY SCHISTOSOMIASIS ON BLOOD HEMOGLOBIN CONCENTRATION OF SCHOOLCHILDREN LIVING IN NORTHERN MOZAMBIQUE
by
Augusto, Gerito
, Nala, Rassul
, Sabonete, Acácio
, Casmo, Verónica
, Carvalho-Costa, Filipe Anibal
in
Anemia
/ Anemia - blood
/ Anemia - parasitology
/ Animals
/ Child
/ Child, Preschool
/ Female
/ Hemoglobin
/ Hemoglobin A - analysis
/ Hookworm Infections - blood
/ Hookworm Infections - complications
/ Hookworms
/ Humans
/ Male
/ Mozambique
/ Schistosoma haematobium
/ Schistosomiasis
/ Schistosomiasis haematobia - blood
/ Schistosomiasis haematobia - complications
/ Severity of Illness Index
/ TROPICAL MEDICINE
2014
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THE EFFECT OF HOOKWORM INFECTION AND URINARY SCHISTOSOMIASIS ON BLOOD HEMOGLOBIN CONCENTRATION OF SCHOOLCHILDREN LIVING IN NORTHERN MOZAMBIQUE
by
Augusto, Gerito
, Nala, Rassul
, Sabonete, Acácio
, Casmo, Verónica
, Carvalho-Costa, Filipe Anibal
in
Anemia
/ Anemia - blood
/ Anemia - parasitology
/ Animals
/ Child
/ Child, Preschool
/ Female
/ Hemoglobin
/ Hemoglobin A - analysis
/ Hookworm Infections - blood
/ Hookworm Infections - complications
/ Hookworms
/ Humans
/ Male
/ Mozambique
/ Schistosoma haematobium
/ Schistosomiasis
/ Schistosomiasis haematobia - blood
/ Schistosomiasis haematobia - complications
/ Severity of Illness Index
/ TROPICAL MEDICINE
2014
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THE EFFECT OF HOOKWORM INFECTION AND URINARY SCHISTOSOMIASIS ON BLOOD HEMOGLOBIN CONCENTRATION OF SCHOOLCHILDREN LIVING IN NORTHERN MOZAMBIQUE
by
Augusto, Gerito
, Nala, Rassul
, Sabonete, Acácio
, Casmo, Verónica
, Carvalho-Costa, Filipe Anibal
in
Anemia
/ Anemia - blood
/ Anemia - parasitology
/ Animals
/ Child
/ Child, Preschool
/ Female
/ Hemoglobin
/ Hemoglobin A - analysis
/ Hookworm Infections - blood
/ Hookworm Infections - complications
/ Hookworms
/ Humans
/ Male
/ Mozambique
/ Schistosoma haematobium
/ Schistosomiasis
/ Schistosomiasis haematobia - blood
/ Schistosomiasis haematobia - complications
/ Severity of Illness Index
/ TROPICAL MEDICINE
2014
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THE EFFECT OF HOOKWORM INFECTION AND URINARY SCHISTOSOMIASIS ON BLOOD HEMOGLOBIN CONCENTRATION OF SCHOOLCHILDREN LIVING IN NORTHERN MOZAMBIQUE
Journal Article
THE EFFECT OF HOOKWORM INFECTION AND URINARY SCHISTOSOMIASIS ON BLOOD HEMOGLOBIN CONCENTRATION OF SCHOOLCHILDREN LIVING IN NORTHERN MOZAMBIQUE
2014
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Overview
This study aims to assess the association between schistosomiasis and hookworm infection with hemoglobin levels of schoolchildren in northern Mozambique. Through a cross-sectional survey, 1,015 children from five to 12 years old in the provinces of Nampula, Cabo Delgado and Niassa were studied. Hookworm infection and urinary schistosomiasis were diagnosed, through Ritchie and filtration methods, with a prevalence of 31.3% and 59.1%, respectively. Hemoglobin levels were obtained with a portable photometer (Hemocue®). The average hemoglobin concentration was 10.8 ± 1.42 g/dL, and 62.1% of the children presented levels below 11.5 g/dL, of which 11.8% of the total number of children had hemoglobin levels below 9 g/dL. A multiple linear regression analysis demonstrated negative interactions between hemoglobin levels and ancylostomiasis, this being restricted to the province of Cabo Delgado (β = -0.55; p < 0.001) where an independent interaction between hemoglobin levels and urinary schistosomiasis was also observed (β = -0.35; p = 0.016). The logistical regression model indicated that hookworm infection represents a predictor of mild (OR = 1.87; 95% CI = 1.17-3.00) and moderate/severe anemia (OR = 2.71; 95% CI = 1.50 - 4.89). We concluded that, in the province of Cabo Delgado, hookworm and Schistosoma haematobium infections negatively influence hemoglobin levels in schoolchildren. Periodical deworming should be considered in the region. Health education and improvements in sanitary infrastructure could achieve long-term and sustainable reductions in soil-transmitted helminthiases and schistosomiasis prevalence rates. Este estudo tem como objetivo avaliar a relação entre a ancilostomíase e a esquistossomíase urinária com as concentrações sanguíneas de hemoglobina em crianças escolares no norte de Moçambique. Em estudo transversal, 1.015 crianças com idade entre cinco e 12 anos foram incluídas, nas Províncias de Nampula, Cabo Delgado e Niassa. A ancilostomíase e a esquistossomíase urinária foram diagnosticadas através das técnicas de Ritchie e de filtração da urina, respectivamente; prevalências de 31,3% e 59,1% foram observadas. As concentrações sanguíneas de hemoglobina foram obtidas com um fotômetro portátil (Hemocue). A concentração média de hemoglobina foi 10,8 ± 1.42 g/dL, 62,1% das crianças apresentaram concentração abaixo de 11,5 g/dL e 11,8% apresentaram nível abaixo de 9 g/dL. A regressão linear múltipla demonstrou interações negativas entre os níveis de hemoglobina e i) a infecção por ancilostomídeos (β = -0,55; p < 0,001) e ii) a esquistossomíase urinária (β = -0,35; p = 0,016), ambas associações restritas à Província de Cabo Delgado. Também em Cabo Delgado, o modelo de regressão logística demonstrou que a infecção por ancilostomídeos representa um preditor de anemia leve (OR = 1,87; 95% CI = 1,17-3,00) e anemia moderada/grave (OR = 2,71; 95% CI = 1,50 - 4,89). O estudo conclui que em Cabo Delgado, Moçambique, as infecções por ancilostomídeos e Schistosoma haematobium estão significativamente associadas a uma menor concentração sanguínea de hemoglobina em crianças em idade escolar. A administração periódica de anti-helmínticos deve ser feita regularmente. Melhorias na infraestrutura sanitária das regiões estudadas são as medidas mais eficazes para controle destas parasitoses.
Publisher
Instituto de Medicina Tropical de Sao Paulo,Instituto de Medicina Tropical,Universidade de São Paulo (USP)
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