Asset Details
Do you wish to reserve the book?
Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration
Do you wish to request the book?
Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Limbal Stem-Cell Therapy and Long-Term Corneal Regeneration
2010
Overview
Corneal damage may become permanent if the supply of limbal stem cells is compromised. In this long-term follow-up study of 113 eyes treated with autologous transplantation of limbal stem-cell cultures, a transparent, renewing corneal epithelium was restored in 77% of eyes and remained stable over time.
Corneal damage may become permanent if the supply of limbal stem cells is compromised. In this long-term follow-up study of 113 eyes treated with autologous transplantation of limbal stem-cell cultures, a transparent, renewing corneal epithelium was restored in 77% of eyes and remained stable over time.
A clear cornea is essential to visual acuity and depends on stromal avascularity and epithelial integrity.
1
Corneal renewal and repair are mediated by stem cells of the limbus, the narrow zone between the cornea and the bulbar conjunctiva.
2
Ocular burns may destroy the limbus, causing limbal stem-cell deficiency. In such cases, the cornea acquires an epithelium through the invasion of bulbar conjunctival cells. This process leads to neovascularization, chronic inflammation, and stromal scarring, with corneal opacity and loss of vision.
3
Allogeneic corneal transplantation (keratoplasty) restores transparency temporarily, but eventually, the conjunctival cells begin to invade and resurface the cornea. The . . .
Publisher
Massachusetts Medical Society
Subject
/ Adult
/ Aged
/ Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
/ Applied cell therapy and gene therapy
/ Biological and medical sciences
/ Corneal Transplantation - methods
/ Endothelium, Corneal - physiology
/ Eye Burns - chemically induced
/ Eye Infections, Bacterial - therapy
/ Female
/ Humans
/ Male
/ Stem Cell Transplantation - methods
/ Transfusions. Complications. Transfusion reactions. Cell and gene therapy
