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Prospective Trial of a Pediatric Ventricular Assist Device
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Prospective Trial of a Pediatric Ventricular Assist Device
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Journal Article
Prospective Trial of a Pediatric Ventricular Assist Device
2012
Overview
In a single-group trial, 48 children with severe heart failure received a ventricular assist device designed for children. Survival rates were significantly higher in this group than among propensity-score–matched children receiving support with extracorporeal membrane oxygenation.
Systolic heart failure causes 280,000 deaths in adults annually in the United States.
1
Heart failure is much less common among children than among adults, but it is highly lethal, with 46% of children with heart failure dying or undergoing transplantation within 5 years after diagnosis, according to one estimate.
2
The survival rate among children after heart transplantation is estimated at 83% at 3 years,
3
,
4
but the limited availability of donor hearts for children prolongs the waiting period,
5
resulting in a high rate of death among children on waiting lists.
6
–
8
Options for mechanical circulatory support as a bridge to . . .
Publisher
Massachusetts Medical Society
Subject
/ Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
/ Biological and medical sciences
/ Bleeding
/ Child
/ Children
/ Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care
/ Extracorporeal Membrane Oxygenation
/ Heart Failure, Systolic - mortality
/ Heart Failure, Systolic - therapy
/ Heart-Assist Devices - adverse effects
/ Humans
/ Outcome Assessment (Health Care)
/ Survival
/ Weaning
