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Percutaneous Closure of Patent Foramen Ovale in Cryptogenic Embolism
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Percutaneous Closure of Patent Foramen Ovale in Cryptogenic Embolism
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Journal Article
Percutaneous Closure of Patent Foramen Ovale in Cryptogenic Embolism
2013
Overview
In this trial, patients with patent foramen ovale and cryptogenic embolism were assigned to undergo closure with the use of a percutaneous device or to receive medical therapy. There was no significant difference in the rates of recurrent embolic events or death.
Paradoxical embolism by means of a patent foramen ovale has been blamed as a cause of stroke and other systemic ischemic events since the 19th century.
1
The actual passage of a venous clot through a patent foramen ovale has been documented in a few cases and resulted in systemic embolic events such as ischemic stroke, transient ischemic attack (TIA),
2
–
6
or myocardial infarction.
7
Catheter-based closure of patent foramen ovale was introduced in 1992.
8
Observational long-term data suggest that closure of patent foramen ovale in patients with a history of ischemic stroke may reduce the risk of recurrent stroke as compared . . .
Publisher
Massachusetts Medical Society
Subject
/ Biological and medical sciences
/ Cardiac Catheterization - adverse effects
/ Congenital heart diseases. Malformations of the aorta, pulmonary vessels and vena cava
/ Embolism
/ Embolism - prevention & control
/ Female
/ Fibrinolytic Agents - adverse effects
/ Fibrinolytic Agents - therapeutic use
/ Foramen Ovale, Patent - complications
/ Foramen Ovale, Patent - drug therapy
/ Foramen Ovale, Patent - mortality
/ Foramen Ovale, Patent - therapy
/ Heart
/ Humans
/ Ischemia
/ Ischemic Attack, Transient - etiology
/ Male
/ Respiratory system : syndromes and miscellaneous diseases
/ Risk
/ Septal Occluder Device - adverse effects
/ Stroke
