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Taking Stock of Retinal Gene Therapy: Looking Back and Moving Forward
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Taking Stock of Retinal Gene Therapy: Looking Back and Moving Forward
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Journal Article
Taking Stock of Retinal Gene Therapy: Looking Back and Moving Forward
2017
Overview
Over the past 20 years, there has been tremendous progress in retinal gene therapy. The safety and efficacy results in one early-onset severe blinding disease may lead to the first gene therapy drug approval in the United States. Here, we review how far the field has come over the past two decades and speculate on the directions that the field will take in the future.
There has been tremendous progress in retinal gene therapy over the past two decades. This progress and the current status of retinal gene therapy are reviewed. Furthermore, there is speculation as to the future directions of this field.
Publisher
Elsevier Inc,Elsevier Limited,American Society of Gene & Cell Therapy
Subject
Adenoviruses, Human - genetics
/ Adenoviruses, Human - metabolism
/ Age
/ Animals
/ Disease
/ Genetic Vectors - administration & dosage
/ Genetic Vectors - metabolism
/ Humans
/ Mutation
/ Peptides
/ Respiratory distress syndrome
/ Retina
/ Retinal Diseases - metabolism
/ Retinal Diseases - pathology
/ Review
