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Randomized Trial of Stent versus Surgery for Asymptomatic Carotid Stenosis
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Randomized Trial of Stent versus Surgery for Asymptomatic Carotid Stenosis
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Journal Article
Randomized Trial of Stent versus Surgery for Asymptomatic Carotid Stenosis
2016
Overview
In this trial involving asymptomatic patients with severe carotid stenosis, stenting was noninferior to endarterectomy with regard to the primary composite end point of death, stroke, or myocardial infarction within 30 days or ipsilateral stroke within 1 year after the procedure.
Stroke is the fifth leading cause of death and the leading cause of disability among U.S. adults. It affects nearly 800,000 people in the United States annually, resulting in more than 170,000 deaths and causing major disability among the survivors, at a cost estimated to exceed $41 billion annually.
1
Extracranial carotid-artery disease is responsible for up to 20% of these strokes. The Asymptomatic Carotid Atherosclerosis Stenosis (ACAS) and Asymptomatic Carotid Surgery (ACST) trials showed that among asymptomatic patients with carotid-artery stenosis of greater than 60% of the diameter of the artery, the risk of stroke or death was lower when . . .
Publisher
Massachusetts Medical Society
Subject
/ Aged
/ Angioplasty - adverse effects
/ Anticoagulants - therapeutic use
/ Carotid Stenosis - complications
/ Carotid Stenosis - mortality
/ Endarterectomy, Carotid - adverse effects
/ Female
/ Humans
/ Implants
/ Ischemia
/ Male
/ Stenosis
/ Stents
/ Stroke - prevention & control
/ Surgery
/ Survival
