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Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation

by Yung, Derek , Lockwood, Evan , Wells, George A , Jolly, Umjeet , Novak, Paul , Essebag, Vidal , Skanes, Allan , Lauck, Sandra , Macle, Laurent , Deyell, Marc W , Khaykin, Yaariv , Verma, Atul , Champagne, Jean , Roux, Jean-Francois , Wardell, Stephan , Andrade, Jason G , Morillo, Carlos , Bennett, Matthew , Sapp, John , Amit, Guy , Angaran, Paul

in Ablation / Adult / Adverse events / Aged / Anti-Arrhythmia Agents - adverse effects / Anti-Arrhythmia Agents - therapeutic use / Antiarrhythmics / Arrhythmia / Atrial Fibrillation - drug therapy / Atrial Fibrillation - prevention & control / Atrial Fibrillation - surgery / Atrial Flutter / Balloon treatment / Cardiac arrhythmia / Catheter Ablation - adverse effects / Catheters / Cryosurgery / Drug dosages / Drug therapy / Female / Fibrillation / Heart / Heart Rate / Humans / Kaplan-Meier Estimate / Male / Middle Aged / Monitoring systems / Monitoring, Physiologic / Patients / Proportional Hazards Models / Quality of Life / Recurrence / Secondary Prevention / Single-Blind Method / Statistical analysis / Tachyarrhythmia / Tachycardia

2021

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2021

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2021

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Journal Article

Cryoablation or Drug Therapy for Initial Treatment of Atrial Fibrillation

Yung, Derek,

Lockwood, Evan,

Wells, George A,

Jolly, Umjeet,

Novak, Paul,

Essebag, Vidal,

Skanes, Allan,

Lauck, Sandra,

Macle, Laurent,

Deyell, Marc W,

Khaykin, Yaariv,

Verma, Atul,

Champagne, Jean,

Roux, Jean-Francois,

Wardell, Stephan,

Andrade, Jason G,

Morillo, Carlos,

Bennett, Matthew,

Sapp, John,

Amit, Guy,

Angaran, Paul

2021

Overview

Patients with symptomatic, paroxysmal, untreated atrial fibrillation were randomly assigned to antiarrhythmic drug therapy or cryoablation. At 1 year, there was a significantly lower rate of recurrence of atrial fibrillation with cryoablation than with drug therapy.

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Publisher

Massachusetts Medical Society

Subject

Ablation

/ Adult

/ Adverse events

/ Aged

/ Anti-Arrhythmia Agents - adverse effects

/ Anti-Arrhythmia Agents - therapeutic use

/ Antiarrhythmics