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Fish Oil–Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring

by Vinding, Rebecca K , Thorsen, Jonathan , Fink, Nadia R , Stark, Ken D , Pedersen, Tine M , Rasmussen, Morten A , Stokholm, Jakob , Schoos, Ann-Marie M , Bønnelykke, Klaus , Bisgaard, Hans , Wolsk, Helene M , Chawes, Bo L , Følsgaard, Nilofar V , Pedersen, Anders G , Bjarnadóttir, Elin , Thorsteinsdóttir, Sunna , Waage, Johannes , Vissing, Nadja H , Olsen, Sjurdur F

in Asthma / Asthma - epidemiology / Asthma - prevention & control / Blood levels / Child, Preschool / Children / Childrens health / Clinical trials / Dietary Supplements / Docosahexaenoic acid / Double-Blind Method / Eczema / Eicosapentaenoic acid / Fatty acids / Fatty Acids, Omega-3 - administration & dosage / Fatty Acids, Omega-3 - blood / Female / Fish oils / Fish Oils - administration & dosage / Follow-Up Studies / Gestation / Humans / Kaplan-Meier Estimate / Male / Medication Adherence / Offspring / Olive oil / Olive Oil - administration & dosage / Phenotyping / Polyunsaturated fatty acids / Pregnancy / Pregnancy Trimester, Third / Preventive medicine / Respiratory Sounds - drug effects / Respiratory tract diseases / Respiratory Tract Infections - epidemiology / Respiratory Tract Infections - prevention & control / Risk / Statistical analysis / Supplements / Wheezing

2016

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2016

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2016

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Journal Article

Fish Oil–Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring

Vinding, Rebecca K,

Thorsen, Jonathan,

Fink, Nadia R,

Stark, Ken D,

Pedersen, Tine M,

Rasmussen, Morten A,

Stokholm, Jakob,

Schoos, Ann-Marie M,

Bønnelykke, Klaus,

Bisgaard, Hans,

Wolsk, Helene M,

Chawes, Bo L,

Følsgaard, Nilofar V,

Pedersen, Anders G,

Bjarnadóttir, Elin,

Thorsteinsdóttir, Sunna,

Waage, Johannes,

Vissing, Nadja H,

Olsen, Sjurdur F

2016

Overview

Supplementation with fish oil–derived fatty acids during pregnancy reduced the incidence of cases of persistent wheeze or asthma in offspring. The incidence of asthma and wheezing disorders has more than doubled in westernized countries in recent decades. 1 These conditions often originate in early childhood 2 and currently affect one in five young children. 3 Concomitantly, the increased use of vegetable oils in cooking and of grain in the feeding of livestock has resulted in an increase in the intake of n−6 polyunsaturated fatty acids and a decrease in the intake of n−3 polyunsaturated fatty acids, especially the long-chain polyunsaturated fatty acids (LCPUFAs) — eicosapentaenoic acid (20:5n–3, EPA) and docosahexaenoic acid (22:6n–3, DHA) — found in cold-water fish. 4 Observational studies have suggested an . . .

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Publisher

Massachusetts Medical Society

Subject

Asthma

/ Asthma - epidemiology

/ Asthma - prevention & control