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High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure
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High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure
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Journal Article
High-Flow Oxygen through Nasal Cannula in Acute Hypoxemic Respiratory Failure
2015
Overview
Patients with acute hypoxemic respiratory failure were assigned to standard oxygen therapy, high-flow oxygen therapy, or noninvasive ventilation. The intubation rate did not differ significantly among the groups, but 90-day mortality was lower in the high-flow–oxygen group.
Noninvasive positive-pressure ventilation (hereafter, noninvasive ventilation) reduces the need for endotracheal intubation and mortality among patients with acute exacerbations of chronic obstructive pulmonary disease
1
–
3
or severe cardiogenic pulmonary edema.
4
The physiological effects of noninvasive ventilation include a decrease in the work of breathing and improvement in gas exchange. In patients with acute hypoxemic respiratory failure, the need for mechanical ventilation is associated with high mortality,
5
but data on the overall effects of noninvasive ventilation with respect to the prevention of intubation and improvement in outcome are conflicting.
6
–
10
Previous studies have often included a heterogeneous population of patients with . . .
Publisher
Massachusetts Medical Society
Subject
/ Adult
/ Aged
/ Female
/ Humans
/ Intubation, Intratracheal - statistics & numerical data
/ Male
/ Nose
/ Oxygen
/ Oxygen - administration & dosage
/ Oxygen Inhalation Therapy - instrumentation
/ Oxygen Inhalation Therapy - methods
/ Patients
/ Positive-Pressure Respiration - instrumentation
/ Respiratory Insufficiency - complications
/ Respiratory Insufficiency - mortality
