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Commentary: Structural and functional features of central nervous system lymphatic vessels
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Journal Article
Commentary: Structural and functional features of central nervous system lymphatic vessels
2015
Overview
Genetic contributions to autism are extremely heterogeneous and may involve synaptic formation and maturation. [...]multiple genes involved in the formation, specification, and maintenance of synapses have been identified as risk factors for ASD development (Hahn et al., 2013). [...]transcranial ultrasonography deserves more attention as a harmless and low-cost means of evaluating CSF fluid volumes and stratifying ASD children potentially at-risk for chronic CNS inflammatory disorders. Transcranial ultrasonography enables reproducible evaluation of EAF by measuring the distances between the arachnoid membrane and the cortical pia layer (subarachnoid space), and may thus help establishing the degree of meningeal lymphatic drainage deficit. Since the measures can be easily repeated, the technique could be used for monitoring the progression of the disease or for objectively assessing the efficacy of treatments. [...]the observation by Louveau et al.
Publisher
Frontiers Research Foundation,Frontiers Media S.A
Subject
