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Antitumor, Antiviral, and Anti-Inflammatory Efficacy of Essential Oils from Atractylodes macrocephala Koidz. Produced with Different Processing Methods
by
Wang, Bing
, Gu, Sihao
, Zhang, Tong
, Huang, Hai
, Li, Ling
in
Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - pharmacology
/ Antineoplastic Agents - chemistry
/ Antineoplastic Agents - pharmacology
/ Antiviral Agents - chemistry
/ Antiviral Agents - pharmacology
/ Antiviral drugs
/ Apoptosis
/ Atractylodes - chemistry
/ Atractylodes macrocephala Koidz
/ atractylone
/ Cancer
/ Cell cycle
/ Chemical Fractionation
/ Cytotoxicity
/ Drug efficacy
/ Essential oils
/ Gas Chromatography-Mass Spectrometry
/ GC/MS
/ Influenza
/ Oils & fats
/ Oils, Volatile - chemistry
/ Oils, Volatile - isolation & purification
/ Oils, Volatile - pharmacology
/ pharmacodynamic effect
/ Phytochemicals - chemistry
/ Phytochemicals - pharmacology
/ Plant Oils - chemistry
/ Plant Oils - isolation & purification
/ Plant Oils - pharmacology
/ processing methods
/ Spleen
/ Traditional Chinese medicine
2019
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Antitumor, Antiviral, and Anti-Inflammatory Efficacy of Essential Oils from Atractylodes macrocephala Koidz. Produced with Different Processing Methods
by
Wang, Bing
, Gu, Sihao
, Zhang, Tong
, Huang, Hai
, Li, Ling
in
Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - pharmacology
/ Antineoplastic Agents - chemistry
/ Antineoplastic Agents - pharmacology
/ Antiviral Agents - chemistry
/ Antiviral Agents - pharmacology
/ Antiviral drugs
/ Apoptosis
/ Atractylodes - chemistry
/ Atractylodes macrocephala Koidz
/ atractylone
/ Cancer
/ Cell cycle
/ Chemical Fractionation
/ Cytotoxicity
/ Drug efficacy
/ Essential oils
/ Gas Chromatography-Mass Spectrometry
/ GC/MS
/ Influenza
/ Oils & fats
/ Oils, Volatile - chemistry
/ Oils, Volatile - isolation & purification
/ Oils, Volatile - pharmacology
/ pharmacodynamic effect
/ Phytochemicals - chemistry
/ Phytochemicals - pharmacology
/ Plant Oils - chemistry
/ Plant Oils - isolation & purification
/ Plant Oils - pharmacology
/ processing methods
/ Spleen
/ Traditional Chinese medicine
2019
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Antitumor, Antiviral, and Anti-Inflammatory Efficacy of Essential Oils from Atractylodes macrocephala Koidz. Produced with Different Processing Methods
by
Wang, Bing
, Gu, Sihao
, Zhang, Tong
, Huang, Hai
, Li, Ling
in
Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - pharmacology
/ Antineoplastic Agents - chemistry
/ Antineoplastic Agents - pharmacology
/ Antiviral Agents - chemistry
/ Antiviral Agents - pharmacology
/ Antiviral drugs
/ Apoptosis
/ Atractylodes - chemistry
/ Atractylodes macrocephala Koidz
/ atractylone
/ Cancer
/ Cell cycle
/ Chemical Fractionation
/ Cytotoxicity
/ Drug efficacy
/ Essential oils
/ Gas Chromatography-Mass Spectrometry
/ GC/MS
/ Influenza
/ Oils & fats
/ Oils, Volatile - chemistry
/ Oils, Volatile - isolation & purification
/ Oils, Volatile - pharmacology
/ pharmacodynamic effect
/ Phytochemicals - chemistry
/ Phytochemicals - pharmacology
/ Plant Oils - chemistry
/ Plant Oils - isolation & purification
/ Plant Oils - pharmacology
/ processing methods
/ Spleen
/ Traditional Chinese medicine
2019
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Antitumor, Antiviral, and Anti-Inflammatory Efficacy of Essential Oils from Atractylodes macrocephala Koidz. Produced with Different Processing Methods
Journal Article
Antitumor, Antiviral, and Anti-Inflammatory Efficacy of Essential Oils from Atractylodes macrocephala Koidz. Produced with Different Processing Methods
2019
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Overview
Atractylodes macrocephala Koidz. has been used as an invigorating spleen drug for eliminating dampness and phlegm in China. According to recent researches, different processing methods may affect the drug efficacy, so we collected A. macrocephala from the Zhejiang Province, produced with different processing methods, crude A. macrocephala (CA) and bran-processed A. macrocephala (BA), then analyzed its essential oils (EOs) by GC/MS. The results showed 34 components representing 98.44% of the total EOs of CA were identified, and 46 components representing 98.02% of the total EOs of BA were identified. Atractylone is the main component in A. macrocephala. Compared with CA, BA has 46 detected compounds, 28 of which were identical, and 6 undetected compounds. Pharmacodynamic results revealed that the EOs of CA and atractylone exhibited more effective anticancer activity in HepG2, MCG803, and HCT-116 cells than the EOs of BA; while the EOs of BA exhibited simple antiviral effect on viruses H3N2, both the EOs and atractylone show anti-inflammatory activity by inhibiting the lipopolysaccharide (LPS)-induced nitric oxide (NO) production in ANA-1 cells.
Publisher
MDPI AG,MDPI
Subject
Anti-Inflammatory Agents - chemistry
/ Anti-Inflammatory Agents - pharmacology
/ Antineoplastic Agents - chemistry
/ Antineoplastic Agents - pharmacology
/ Antiviral Agents - chemistry
/ Antiviral Agents - pharmacology
/ Atractylodes macrocephala Koidz
/ Cancer
/ Gas Chromatography-Mass Spectrometry
/ GC/MS
/ Oils, Volatile - isolation & purification
/ Oils, Volatile - pharmacology
/ Phytochemicals - pharmacology
/ Plant Oils - isolation & purification
/ Spleen
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