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Paclitaxel-Eluting or Sirolimus-Eluting Stents to Prevent Restenosis in Diabetic Patients
by
Wessely, Rainer
, Schömig, Albert
, Schühlen, Helmut
, Mehilli, Julinda
, Kastrati, Adnan
, Dibra, Alban
, Pache, Jürgen
, Ulm, Kurt
, Dirschinger, Josef
, von Beckerath, Nicolas
in
Aged
/ Angina pectoris
/ Angioplasty, Balloon, Coronary
/ Biological and medical sciences
/ Cardiovascular disease
/ Coronary Angiography
/ Coronary Disease - mortality
/ Coronary Disease - therapy
/ Coronary Restenosis - epidemiology
/ Coronary Restenosis - prevention & control
/ Coronary Restenosis - therapy
/ Coronary vessels
/ Diabetes Complications - therapy
/ Diabetes. Impaired glucose tolerance
/ Endocrine pancreas. Apud cells (diseases)
/ Endocrinopathies
/ Etiopathogenesis. Screening. Investigations. Target tissue resistance
/ Female
/ Follow-Up Studies
/ General aspects
/ Heart attacks
/ Humans
/ Immunosuppressive Agents - administration & dosage
/ Male
/ Medical sciences
/ Middle Aged
/ Myocardial Infarction - epidemiology
/ Paclitaxel - administration & dosage
/ Regression Analysis
/ Sirolimus - administration & dosage
/ Stents
/ Survival Analysis
2005
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Paclitaxel-Eluting or Sirolimus-Eluting Stents to Prevent Restenosis in Diabetic Patients
by
Wessely, Rainer
, Schömig, Albert
, Schühlen, Helmut
, Mehilli, Julinda
, Kastrati, Adnan
, Dibra, Alban
, Pache, Jürgen
, Ulm, Kurt
, Dirschinger, Josef
, von Beckerath, Nicolas
in
Aged
/ Angina pectoris
/ Angioplasty, Balloon, Coronary
/ Biological and medical sciences
/ Cardiovascular disease
/ Coronary Angiography
/ Coronary Disease - mortality
/ Coronary Disease - therapy
/ Coronary Restenosis - epidemiology
/ Coronary Restenosis - prevention & control
/ Coronary Restenosis - therapy
/ Coronary vessels
/ Diabetes Complications - therapy
/ Diabetes. Impaired glucose tolerance
/ Endocrine pancreas. Apud cells (diseases)
/ Endocrinopathies
/ Etiopathogenesis. Screening. Investigations. Target tissue resistance
/ Female
/ Follow-Up Studies
/ General aspects
/ Heart attacks
/ Humans
/ Immunosuppressive Agents - administration & dosage
/ Male
/ Medical sciences
/ Middle Aged
/ Myocardial Infarction - epidemiology
/ Paclitaxel - administration & dosage
/ Regression Analysis
/ Sirolimus - administration & dosage
/ Stents
/ Survival Analysis
2005
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Paclitaxel-Eluting or Sirolimus-Eluting Stents to Prevent Restenosis in Diabetic Patients
by
Wessely, Rainer
, Schömig, Albert
, Schühlen, Helmut
, Mehilli, Julinda
, Kastrati, Adnan
, Dibra, Alban
, Pache, Jürgen
, Ulm, Kurt
, Dirschinger, Josef
, von Beckerath, Nicolas
in
Aged
/ Angina pectoris
/ Angioplasty, Balloon, Coronary
/ Biological and medical sciences
/ Cardiovascular disease
/ Coronary Angiography
/ Coronary Disease - mortality
/ Coronary Disease - therapy
/ Coronary Restenosis - epidemiology
/ Coronary Restenosis - prevention & control
/ Coronary Restenosis - therapy
/ Coronary vessels
/ Diabetes Complications - therapy
/ Diabetes. Impaired glucose tolerance
/ Endocrine pancreas. Apud cells (diseases)
/ Endocrinopathies
/ Etiopathogenesis. Screening. Investigations. Target tissue resistance
/ Female
/ Follow-Up Studies
/ General aspects
/ Heart attacks
/ Humans
/ Immunosuppressive Agents - administration & dosage
/ Male
/ Medical sciences
/ Middle Aged
/ Myocardial Infarction - epidemiology
/ Paclitaxel - administration & dosage
/ Regression Analysis
/ Sirolimus - administration & dosage
/ Stents
/ Survival Analysis
2005
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Paclitaxel-Eluting or Sirolimus-Eluting Stents to Prevent Restenosis in Diabetic Patients
Journal Article
Paclitaxel-Eluting or Sirolimus-Eluting Stents to Prevent Restenosis in Diabetic Patients
2005
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Overview
Drug-eluting coronary-artery stents are more effective than bare-metal stents in reducing the frequency of coronary restenosis in patients with diabetes. In a randomized, controlled trial in patients with diabetes, the sirolimus-eluting stent was associated with a smaller extent of late luminal loss than was the paclitaxel-eluting stent, suggesting that the risk of restenosis was also reduced.
In patients with diabetes, the sirolimus-eluting stent was associated with a smaller extent of late luminal loss than was the paclitaxel-eluting stent, suggesting that the risk of restenosis was also reduced.
Coronary artery disease is a major cause of complications and death among patients with diabetes mellitus.
1
In particular, patients with diabetes are prone to a diffuse and rapidly progressive form of atherosclerosis, which increases their likelihood of requiring revascularization.
2
–
4
Percutaneous coronary intervention and aortocoronary bypass surgery are recommended revascularization strategies for such patients. However, because of the increased risk of restenosis after percutaneous coronary interventions in these patients,
5
–
7
aortocoronary bypass surgery has been considered to be the preferred revascularization strategy for many.
8
,
9
Drug-eluting stents markedly reduce the incidence of restenosis as compared with bare-metal stents, both in . . .
Publisher
Massachusetts Medical Society
Subject
/ Angioplasty, Balloon, Coronary
/ Biological and medical sciences
/ Coronary Disease - mortality
/ Coronary Restenosis - epidemiology
/ Coronary Restenosis - prevention & control
/ Coronary Restenosis - therapy
/ Diabetes Complications - therapy
/ Diabetes. Impaired glucose tolerance
/ Endocrine pancreas. Apud cells (diseases)
/ Etiopathogenesis. Screening. Investigations. Target tissue resistance
/ Female
/ Humans
/ Immunosuppressive Agents - administration & dosage
/ Male
/ Myocardial Infarction - epidemiology
/ Paclitaxel - administration & dosage
/ Sirolimus - administration & dosage
/ Stents
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