Asset Details
Do you wish to reserve the book?
Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area
Do you wish to request the book?
Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Incidence and survival rate of women with cervical cancer in the Greater Amsterdam area
2003
Overview
To evaluate the effect of population-based cervical cancer screening on the occurrence of cervical cancer in The Netherlands, we investigated the incidence and survival of cervical cancer registered by a cancer registry in the Greater Amsterdam area. The incidence rate of squamous cell carcinoma decreased significantly from 9.2/100 000 women in 1988 to 5.9/100 000 in 2000 (
P
<0.001). The incidence rate of adenocarcinomas remained stable. After adjustment for age, stage and lymph node involvement, the relative risk of death was 1.6 times higher for patients with adenocarcinomas than for patients with squamous cell carcinoma (95% CI 1.2–2.1). The decreased survival was related to histological type, as the effect remained significant after correction for confounding factors. Over time, the prognosis of women with squamous cell carcinoma improved significantly. No significant change was observed for women diagnosed with adenocarcinoma. These results suggest that the screening programme in The Netherlands as executed in the Greater Amsterdam area is associated with a decreased incidence and increased survival of patients with squamous cell carcinoma, but fails to detect (pre)malignant lesions of adenocarcinoma. Since more than 92% of adenocarcinomas and its precursors contain high-risk HPV, adding HPV testing to cytologic screening might improve the present screening programme in detecting adenocarcinoma and its precursor lesions.
Publisher
Nature Publishing Group UK,Nature Publishing Group
Subject
/ Adenocarcinoma/epidemiology/mortality/pathology
/ Adult
/ Aged
/ Biomedical and Life Sciences
/ Carcinoma, Squamous Cell - epidemiology
/ Carcinoma, Squamous Cell - mortality
/ Carcinoma, Squamous Cell - pathology
/ Carcinoma, Squamous Cell/epidemiology/mortality/pathology
/ Female
/ Genetics & genetic processes
/ Génétique & processus génétiques
/ Humans
/ Oncology
/ Uterine Cervical Neoplasms - epidemiology
/ Uterine Cervical Neoplasms - mortality
/ Uterine Cervical Neoplasms - pathology
/ Uterine Cervical Neoplasms/epidemiology/mortality/pathology
