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Neurodevelopment of Amazonian Infants : Antenatal and Postnatal Exposure to Methyl- and Ethylmercury
by
Isejima, Cintya
, Marques, Rejane C.
, Dorea, Jose G.
in
Animal cognition
/ Aquatic ecosystems
/ Brazil
/ Breast Feeding
/ Breastfeeding & lactation
/ Developmental Disabilities - chemically induced
/ Diet
/ Diet Surveys
/ Ethylmercury Compounds - pharmacokinetics
/ Ethylmercury Compounds - poisoning
/ Families & family life
/ Female
/ Hair - chemistry
/ Hair - metabolism
/ Health facilities
/ Humans
/ Immunization
/ Infant
/ Infant, Newborn
/ Logistic Models
/ Male
/ Maternal Exposure
/ Mercury - analysis
/ Mercury - pharmacokinetics
/ Methylmercury Compounds - pharmacokinetics
/ Methylmercury Compounds - poisoning
/ Mothers
/ Neurotoxicity
/ Nutrition
/ Pregnancy
/ Prenatal Exposure Delayed Effects
/ Psychomotor Performance - drug effects
/ Rural areas
/ Rural Population
/ Socioeconomic Factors
/ Studies
/ Urban Population
/ Vaccines
2012
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Neurodevelopment of Amazonian Infants : Antenatal and Postnatal Exposure to Methyl- and Ethylmercury
by
Isejima, Cintya
, Marques, Rejane C.
, Dorea, Jose G.
in
Animal cognition
/ Aquatic ecosystems
/ Brazil
/ Breast Feeding
/ Breastfeeding & lactation
/ Developmental Disabilities - chemically induced
/ Diet
/ Diet Surveys
/ Ethylmercury Compounds - pharmacokinetics
/ Ethylmercury Compounds - poisoning
/ Families & family life
/ Female
/ Hair - chemistry
/ Hair - metabolism
/ Health facilities
/ Humans
/ Immunization
/ Infant
/ Infant, Newborn
/ Logistic Models
/ Male
/ Maternal Exposure
/ Mercury - analysis
/ Mercury - pharmacokinetics
/ Methylmercury Compounds - pharmacokinetics
/ Methylmercury Compounds - poisoning
/ Mothers
/ Neurotoxicity
/ Nutrition
/ Pregnancy
/ Prenatal Exposure Delayed Effects
/ Psychomotor Performance - drug effects
/ Rural areas
/ Rural Population
/ Socioeconomic Factors
/ Studies
/ Urban Population
/ Vaccines
2012
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Neurodevelopment of Amazonian Infants : Antenatal and Postnatal Exposure to Methyl- and Ethylmercury
by
Isejima, Cintya
, Marques, Rejane C.
, Dorea, Jose G.
in
Animal cognition
/ Aquatic ecosystems
/ Brazil
/ Breast Feeding
/ Breastfeeding & lactation
/ Developmental Disabilities - chemically induced
/ Diet
/ Diet Surveys
/ Ethylmercury Compounds - pharmacokinetics
/ Ethylmercury Compounds - poisoning
/ Families & family life
/ Female
/ Hair - chemistry
/ Hair - metabolism
/ Health facilities
/ Humans
/ Immunization
/ Infant
/ Infant, Newborn
/ Logistic Models
/ Male
/ Maternal Exposure
/ Mercury - analysis
/ Mercury - pharmacokinetics
/ Methylmercury Compounds - pharmacokinetics
/ Methylmercury Compounds - poisoning
/ Mothers
/ Neurotoxicity
/ Nutrition
/ Pregnancy
/ Prenatal Exposure Delayed Effects
/ Psychomotor Performance - drug effects
/ Rural areas
/ Rural Population
/ Socioeconomic Factors
/ Studies
/ Urban Population
/ Vaccines
2012
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Neurodevelopment of Amazonian Infants : Antenatal and Postnatal Exposure to Methyl- and Ethylmercury
Journal Article
Neurodevelopment of Amazonian Infants : Antenatal and Postnatal Exposure to Methyl- and Ethylmercury
2012
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Overview
Neurodevelopment as Gesell development scores (GDSs) in relation to mercury exposure in infants (<6 months of age) of one urban center and two rural villages, respectively, of fisherman and cassiterite miners. Mean total hair-Hg (HHg) concentrations of infants from Itapuã (3.95±1.8 ppm) were statistically (P=0.0001) different from those of infants from Porto Velho (3.84±5.5 ppm) and Bom Futuro (1.85±0.9 ppm). Differences in vaccine coverage among these populations resulted in significantly higher (P=0.0001) mean ethylmercury (EtHg) exposure in urban infants (150 μg) than in infants from either village (41.67 μg, Itapuã; 42.39 μg, Bom Futuro). There was an inverse significant (Spearman r=−0.2300; P=0.0376) correlation between HHg and GDS for infants from Porto Velho, but not for the rural infants from Bom Futuro (Spearman r=0.1336; P=0.0862) and Itapuã (Spearman r=0.1666; P=0.5182). Logistic regression applied to variables above or below the median GDS showed that EtHg exposure (estimated probability=−0.0157; P=0.0070) and breastfeeding score (estimated probability=−0.0066; P=0.0536) score were significantly associated with GDS. Conclusion. In nurslings whose mothers are exposed to different levels of fish-MeHg (HHg), a higher score of neurological development at six months was negatively associated with exposure to additional TCV-EtHg. Results should be interpreted with caution because of unaccounted variables.
Publisher
Hindawi Puplishing Corporation,Hindawi Publishing Corporation,John Wiley & Sons, Inc
Subject
/ Brazil
/ Developmental Disabilities - chemically induced
/ Diet
/ Ethylmercury Compounds - pharmacokinetics
/ Ethylmercury Compounds - poisoning
/ Female
/ Humans
/ Infant
/ Male
/ Methylmercury Compounds - pharmacokinetics
/ Methylmercury Compounds - poisoning
/ Mothers
/ Prenatal Exposure Delayed Effects
/ Psychomotor Performance - drug effects
/ Studies
/ Vaccines
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