Asset Details
Do you wish to reserve the book?
Electrocardiographic precedence with rapid anatomical progression in apical hypertrophic cardiomyopathy: a case report
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Electrocardiographic precedence with rapid anatomical progression in apical hypertrophic cardiomyopathy: a case report
Do you wish to request the book?
Electrocardiographic precedence with rapid anatomical progression in apical hypertrophic cardiomyopathy: a case report
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Electrocardiographic precedence with rapid anatomical progression in apical hypertrophic cardiomyopathy: a case report
2025
Overview
Deep T-wave inversion (TWI) in the mid- to lateral precordial leads is a recognized electrocardiographic marker of apical hypertrophic cardiomyopathy (ApHCM), although its temporal trajectory is variable. We report a 39-year-old hypertensive, non-athlete male who exhibited stable, low-amplitude biphasic T waves for four years, followed by rapid progression in the fifth year to giant, asymmetric TWI (10 mm). At the onset of this escalation, transthoracic echocardiography revealed relatively increased apical wall thickness compared with basal segments, although still within normative limits, which may represent an early phenotypic cue of ApHCM that was not clinically recognized. Subsequent echocardiography confirmed ApHCM, and cardiac magnetic resonance (CMR) substantiated isolated apical hypertrophy, indicating electro-anatomical conversion during the fifth year despite well-controlled blood pressure. This case highlights that rapid TWI progression following prolonged quiescence should prompt clinical suspicion for ApHCM. Given the potential for false-negative echocardiographic findings, close surveillance and timely CMR are essential for definitive diagnosis.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Adult
/ Analysis
/ Antihypertensive Agents - therapeutic use
/ Apical Hypertrophic Cardiomyopathy
/ Cardiomyopathy, Hypertrophic
/ Cardiomyopathy, Hypertrophic - diagnosis
/ Cardiomyopathy, Hypertrophic - diagnostic imaging
/ Cardiomyopathy, Hypertrophic - etiology
/ Cardiomyopathy, Hypertrophic - physiopathology
/ Electrocardiogram monitoring
/ Electro‑anatomical dissociation
/ Humans
/ Hypertension - complications
/ Hypertension - physiopathology
/ Ischemia
/ Magnetic resonance angiography
/ Male
/ Medicine
