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The Influence of Obesity on Bone Health in Post-COVID-19 Recovery- Single-Center Experience
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The Influence of Obesity on Bone Health in Post-COVID-19 Recovery- Single-Center Experience
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Journal Article
The Influence of Obesity on Bone Health in Post-COVID-19 Recovery- Single-Center Experience
2024
Overview
The ongoing repercussions of the COVID-19 pandemic include potentially deleterious impacts on bone health.
This research aimed to ascertain the effects of COVID-19 on the bone health of obese and non-obese Indian individuals.
We executed a case-control study enrolling individuals who recovered from COVID-19. Participants were stratified into obese and non-obese groups based on their BMI. Comprehensive assessments encompassed anthropometric evaluations, laboratory tests, and bone mineral density (BMD) measurements using dual-energy X-ray absorptiometry (DEXA).
From April to July 2022, we enrolled obese (n = 27, mean BMI = 30.54 ± 4.51 kg/m 2) and non-obese (n = 23, mean BMI = 21.97 ± 2.20 kg/m 2) individuals. The cohort's average age was 36.08 ± 15.81 years, with a male-to-female ratio of 1.6:1. There was a difference in BMD, especially at the total hip, between the two groups. BMD at the spine (L1-L4), the neck of the femur, and ultra-distal radius were consistent across both groups. Weight exhibited a significant positive correlation with BMD at L1-L4 (r = 0.40,
= 0.003) and the left femur total (r = 0.27,
= 0.001). Haemoglobin levels were lower in the obese group compared to their non-obese counterparts (12.3 ± 2.0 vs 13.6 ± 1.9,
= 0.01). Multivariate analysis underscored weight as a crucial predictor for BMD at the spine (L1-L4,
= 0.003) and total hip (
= 0.001).
Even with advanced age, obese post-COVID-19 individuals demonstrate a higher bone mineral density (BMD) at the hip than non-obese subjects.
