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Self-help mobile messaging intervention for depression among older adults in resource-limited settings: a randomized controlled trial
by
Moretti, Felipe Azevedo
, Oliveira da Costa, Marcelo
, Queiroz de Souza, Caio Hudson
, Araya, Ricardo
, Didone, Thiago Vinicius Nadaleto
, Macias de Oliveira, Gabriel
, Hollingworth, William
, Mendes de Sá Martins, Mariana
, Seward, Nadine
, Pereira, Luara Aragoni
, van de Ven, Pepijn
, Scazufca, Marcia
, Nakamura, Carina Akemi
, Souza dos Santos, Monica
, Peters, Tim J.
in
692/699/476/1414
/ 692/700/1518
/ Adults
/ Aged
/ Biomedical and Life Sciences
/ Biomedicine
/ Brazil
/ Cancer Research
/ Clinical trials
/ Depression - therapy
/ Female
/ Humans
/ Infectious Diseases
/ Intervention
/ Male
/ Medical personnel
/ Messages
/ Metabolic Diseases
/ Molecular Medicine
/ Neurosciences
/ Older people
/ Primary care
/ Self help
/ Single-Blind Method
2024
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Self-help mobile messaging intervention for depression among older adults in resource-limited settings: a randomized controlled trial
by
Moretti, Felipe Azevedo
, Oliveira da Costa, Marcelo
, Queiroz de Souza, Caio Hudson
, Araya, Ricardo
, Didone, Thiago Vinicius Nadaleto
, Macias de Oliveira, Gabriel
, Hollingworth, William
, Mendes de Sá Martins, Mariana
, Seward, Nadine
, Pereira, Luara Aragoni
, van de Ven, Pepijn
, Scazufca, Marcia
, Nakamura, Carina Akemi
, Souza dos Santos, Monica
, Peters, Tim J.
in
692/699/476/1414
/ 692/700/1518
/ Adults
/ Aged
/ Biomedical and Life Sciences
/ Biomedicine
/ Brazil
/ Cancer Research
/ Clinical trials
/ Depression - therapy
/ Female
/ Humans
/ Infectious Diseases
/ Intervention
/ Male
/ Medical personnel
/ Messages
/ Metabolic Diseases
/ Molecular Medicine
/ Neurosciences
/ Older people
/ Primary care
/ Self help
/ Single-Blind Method
2024
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Self-help mobile messaging intervention for depression among older adults in resource-limited settings: a randomized controlled trial
by
Moretti, Felipe Azevedo
, Oliveira da Costa, Marcelo
, Queiroz de Souza, Caio Hudson
, Araya, Ricardo
, Didone, Thiago Vinicius Nadaleto
, Macias de Oliveira, Gabriel
, Hollingworth, William
, Mendes de Sá Martins, Mariana
, Seward, Nadine
, Pereira, Luara Aragoni
, van de Ven, Pepijn
, Scazufca, Marcia
, Nakamura, Carina Akemi
, Souza dos Santos, Monica
, Peters, Tim J.
in
692/699/476/1414
/ 692/700/1518
/ Adults
/ Aged
/ Biomedical and Life Sciences
/ Biomedicine
/ Brazil
/ Cancer Research
/ Clinical trials
/ Depression - therapy
/ Female
/ Humans
/ Infectious Diseases
/ Intervention
/ Male
/ Medical personnel
/ Messages
/ Metabolic Diseases
/ Molecular Medicine
/ Neurosciences
/ Older people
/ Primary care
/ Self help
/ Single-Blind Method
2024
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Self-help mobile messaging intervention for depression among older adults in resource-limited settings: a randomized controlled trial
Journal Article
Self-help mobile messaging intervention for depression among older adults in resource-limited settings: a randomized controlled trial
2024
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Overview
Scalable solutions to treat depression in older adults in low-resourced settings are urgently needed. The PRODIGITAL-D pragmatic, single-blind, two-arm, individually randomized controlled trial assessed the effectiveness of a mobile messaging psychosocial intervention in improving depressive symptomatology among older adults in socioeconomically deprived areas of Guarulhos, Brazil. Older adults (aged 60+ years) registered with 24 primary care clinics and identified with depressive symptomatology (9-item Patient Health Questionnaire (PHQ-9) scores ≥ 10) received the 6-week Viva Vida intervention based on psychoeducation and behavioral activation (
n
= 298) or a single message (
n
= 305). No health professional support was offered. The primary outcome was improvement from depressive symptomatology (PHQ-9 < 10) at 3 months. Of the 603 participants enrolled (mean age = 65.1 years; 451 (74.8%) women), 527 (87.4%) completed the follow-up assessment. In the intervention arm, 109 of 257 (42.4%) participants had an improved depressive symptomatology, compared with 87 of 270 (32.2%) participants in the control arm (adjusted odds ratio = 1.57; 95% confidence interval = 1.07–2.29;
P
= 0.019). No severe adverse events related to trial participation were observed. These results demonstrate the usefulness of a digital messaging psychosocial intervention in the short-term improvement from depressive symptomatology that can potentially be integrated into primary care programs for treating older adults with depression. Brazilian Registry of Clinical Trials registration: ReBEC (
RBR-4c94dtn
).
The PRODIGITAL-D trial in adults aged 60+ years from socioeconomically deprived areas of Brazil showed that a 6-week self-help mobile messaging psychosocial intervention was effective in improving depression recovery at 3 months compared to a single message control intervention.
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