Asset Details
Do you wish to reserve the book?
Effect of the intermittent Pringle maneuver on liver damage after hepatectomy: a retrospective cohort study
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Effect of the intermittent Pringle maneuver on liver damage after hepatectomy: a retrospective cohort study
Do you wish to request the book?
Effect of the intermittent Pringle maneuver on liver damage after hepatectomy: a retrospective cohort study
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Effect of the intermittent Pringle maneuver on liver damage after hepatectomy: a retrospective cohort study
2019
Overview
Background
The Pringle maneuver (PM) interrupts the blood flow through the hepatic artery and portal vein to help control bleeding. This study analyzes the effects of the intermittent Pringle maneuver (IPM) on the surgical process and postoperative liver injury.
Methods
This study retrospectively evaluated 182 hepatocellular carcinoma patients who underwent hepatectomy. In the IPM group, hepatic blood flow was intermittently interrupted via clamping, with cycles of 10 minutes of inflow occlusion followed by 5 minutes of reperfusion that were repeated until the end of the surgery. In the non-IPM group, liver resection was performed without hepatic vascular blockage.
Results
For postoperative complications, the incidence rates of ascites and pleural effusion in the IPM group were significantly lower than those in the non-IPM group. The postoperative hospitalization time in the IPM group was significantly lower than that in the non-IPM group (
p
=0.0008). On the first day after the operation, the platelet count was significantly lower (
p
=0.0381) but the prothrombin time (PT) (
p
=0.0195) and activated partial thromboplastin time (APTT) (
p
=0.0071) were significantly higher in the non-IPM group than those in the IPM group. At discharge, only albumin was significantly higher in the non-IPM group than that in the IPM group (
p
=0.0303). Regression analysis showed that a prolonged interruption time was related to increased ALT and AST levels on the first day after surgery, but not on the seventh day or at discharge.
Conclusion
The IPM does not cause additional liver damage during hepatectomy, and use of the IPM results in shorter hospital stays compared to surgery without using the IPM. The results of this study require further confirmation because of the retrospective design.
Publisher
BioMed Central,BMC
Subject
/ Aged
/ Blood Loss, Surgical - prevention & control
/ Carcinoma, Hepatocellular - pathology
/ Carcinoma, Hepatocellular - surgery
/ Female
/ Hepatectomy - adverse effects
/ Humans
/ Male
/ Medicine
/ Postoperative Complications - etiology
/ Postoperative Complications - pathology
