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Predictability of Central Corneal Stromal Reduction After SMILE and FS-LASIK for High Myopia Correction: A Prospective Randomized Contralateral Eye Study
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Predictability of Central Corneal Stromal Reduction After SMILE and FS-LASIK for High Myopia Correction: A Prospective Randomized Contralateral Eye Study
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Predictability of Central Corneal Stromal Reduction After SMILE and FS-LASIK for High Myopia Correction: A Prospective Randomized Contralateral Eye Study
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Journal Article
Predictability of Central Corneal Stromal Reduction After SMILE and FS-LASIK for High Myopia Correction: A Prospective Randomized Contralateral Eye Study
2022
Overview
PURPOSE:
To compare small incision lenticule extraction (SMILE) and femtosecond laser–assisted in situ keratomileusis (FS-LASIK) in terms of the predictability of central stromal thickness reduction in eyes with high myopia.
METHODS:
In this prospective, randomized contralateral eye trial, 42 patients received SMILE in one eye and FS-LASIK (using the Amaris 750S excimer laser [SCHWIND eye-tech-solutions]) in the fellow eye for the correction of high myopia (manifest refraction spherical equivalent: < −6.00 diopters). Spectral-domain optical coherence tomography was used to measure the central corneal and epithelial thickness. Pre-operative and postoperative values were compared to determine the amount of central stromal reduction achieved.
RESULTS:
At the 6-month follow-up visit, the amount of central stromal reduction was overestimated by 20.05 ± 5.92 µm in the SMILE group (P < .0001) and underestimated by 8.21 ± 8.14 µm in the FS-LASIK group (P < .0001). The mean actual central stromal reduction achieved with SMILE was significantly less than that achieved with FS-LASIK (10.10 ± 18.01 µm, range: 1.90 to 18.29 µm, P < .001). The discrepancy between the planned and achieved central corneal stromal reduction was not associated with refractive overcorrection or undercorrection in either the SMILE group or the FS-LASIK group (P = .9743 vs P = .0777).
CONCLUSIONS:
In patients with high myopia, the laser software platform may underestimate and overestimate the amount of actual corneal reduction in eyes treated with FS-LASIK and SMILE, respectively. SMILE required less corneal stroma compared to FS-LASIK in the studied cohort using the Amaris 750S excimer laser when correcting a similar spherical equivalent refraction.
[J Refract Surg. 2022;38(2):90–97.]
Publisher
SLACK Incorporated,Slack, Inc,SLACK INCORPORATED
Subject
/ Cornea
/ Eye
/ Humans
/ Keratomileusis, Laser In Situ
/ Lasers
/ Lasers, Excimer - therapeutic use
/ Myopia
/ Patients
/ Surgery
/ Testing
