Journal Article

Join us on an amazing journey towards next‐generation treatments for CNS disorders: Launch of Neuroprotection, a new high‐quality journal in translational neuroscience

Jolkkonen, Jukka, Ji, Xunming, Zille, Marietta, Walczak, Piotr, Casas, Ana I., Li, Shen, Rosado‐de‐Castro, Paulo H., Boltze, Johannes, Liang, Yajie, Farr, Tracy, van Beusekom, Heleen M. M., Modo, Michel M., Ruscher, Karsten, Wang, Yan‐Jiang, Wu, Haitao, Clarkson, Andrew

2023

Overview

Whereas previous preclinical research and the translation of results obtained therein into clinical treatments were often impaired by shortcomings in experimental design, research quality in the field has improved substantially and methodological rigor applied today is outstanding across many fields. Many of these approaches are safe to be applied in a prehospital setting, opening new ways for more targeted and effective ‘2nd generation’ neuroprotective treatment paradigms. [...]these new paradigms are developed to be fully compatible with established treatment procedures including recanalization approaches. [...]a recent double-blind and randomized phase II clinical trial in multiple sclerosis (MS) revealed preliminary evidence for a modest yet clinically meaningful therapeutic effect of mesenchymal stem cell (MSC) transplantation. The article was subject to the journal's standard procedures, with peer review handled independently of this Editorial Board member and their research groups.

• Publisher: John Wiley & Sons, Inc,Beijing Institute of Brain Disorders, Capital Medical University, Beijing, China%Department of Diagnostic Radiology and Nuclear Medicine, Center for Advanced Imaging Research, University of Maryland, Baltimore, Maryland, USA%Department of Cardiology, Erasmus MC Rotterdam, University Medical Center Rotterdam, Rotterdam, The Netherlands%Department of Neurology, Center for Translational Neuro- and Behavioral Sciences (C-TNBS), University Clinics Essen, Essen, Germany%Department of Anatomy, Brain Health Research Center and Brain Research New Zealand, Dunedin, New Zealand%Medical School, Queen's Medical Centre, University of Nottingham, Nottingham, UK%A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland%McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA%Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA%Department of Bioengineering, University of Pittsburgh, Pittsburgh, Pennsylvania, USA%Department of Anatomy and Department of Radiology, School of Medicine, Institute of Biomedical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil%Laboratory for Experimental Brain Research, University of Lund, Lund, Sweden%Department of Neurology, Daping Hospital, Center for Clinical Neuroscience, Chongqing, China%Department of Neurobiology, Beijing Institute of Basic Medical Sciences, Beijing, China%Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, Vienna, Austria%Department of Neurology and Psychiatry, Beijing Shijitan Hospital, Capital Medical University, Beijing, China%School of Life Sciences, University of Warwick, Coventry, UK,John Wiley and Sons Inc,Wiley
• Subject: Basic Medicine / Brain research / Clinical trials / cytoprotection / Disease / Drugs / Medical and Health Sciences / Medical research / Medicin och hälsovetenskap / Medicinska och farmaceutiska grundvetenskaper / Nervous system / nervous system repair / neurodegeneration / neuroprotection / Neurosciences / neurovasculardiseases / Neurovetenskaper / Parkinson's disease / translational research