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Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

by Eaton, Charles B , Radziszewska, Barbara , Shah, Raj C , Mahady, Suzanne E , Nelson, Mark R , Donnan, Geoffrey A , Jelinek, Michael , Grimm, Richard , Woods, Robyn L , Williamson, Jeff D , Fitzgerald, Sharyn M , Orchard, Suzanne G , Ryan, Joanne , Storey, Elsdon , Cloud, Geoff , Lockery, Jessica E , Satterfield, Suzanne , Margolis, Karen L , Reid, Christopher M , Abhayaratna, Walter P , Beilin, Lawrence J , Malik, Mobin , Kirpach, Brenda , McNeil, John J , Brauer, Donna , Ernst, Michael E , Wolfe, Rory , Stocks, Nigel , Trevaks, Ruth E , Tonkin, Andrew M , Wood, Erica M , Murray, Anne M , Johnston, Colin I

in Administration, Oral / Age / Aged / Aged, 80 and over / Aging / Aspirin / Aspirin - adverse effects / Aspirin - therapeutic use / Australia / Blood pressure / Cardiovascular disease / Cardiovascular diseases / Cardiovascular Diseases - epidemiology / Cardiovascular Diseases - mortality / Cardiovascular Diseases - prevention & control / Cerebral infarction / Coronary artery disease / Dementia disorders / Disease prevention / Double-Blind Method / Drug dosages / Epidemiology / Female / Geriatrics / Health care / Health risk assessment / Heart attacks / Heart diseases / Heart failure / Hemorrhage / Hemorrhage - chemically induced / Hemorrhage - epidemiology / Humans / Independent Living / Male / Myocardial infarction / Older people / Platelet Aggregation Inhibitors - adverse effects / Platelet Aggregation Inhibitors - therapeutic use / Preventive medicine / Stroke / Treatment Failure / United States

2018

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2018

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2018

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Journal Article

Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly

Eaton, Charles B,

Radziszewska, Barbara,

Shah, Raj C,

Mahady, Suzanne E,

Nelson, Mark R,

Donnan, Geoffrey A,

Jelinek, Michael,

Grimm, Richard,

Woods, Robyn L,

Williamson, Jeff D,

Fitzgerald, Sharyn M,

Orchard, Suzanne G,

Ryan, Joanne,

Storey, Elsdon,

Cloud, Geoff,

Lockery, Jessica E,

Satterfield, Suzanne,

Margolis, Karen L,

Reid, Christopher M,

Abhayaratna, Walter P,

Beilin, Lawrence J,

Malik, Mobin,

Kirpach, Brenda,

McNeil, John J,

Brauer, Donna,

Ernst, Michael E,

Wolfe, Rory,

Stocks, Nigel,

Trevaks, Ruth E,

Tonkin, Andrew M,

Wood, Erica M,

Murray, Anne M,

Johnston, Colin I

2018

Overview

In older persons without known cardiovascular disease, the use of low-dose aspirin resulted in a significantly higher risk of major hemorrhage and did not result in a significantly lower risk of cardiovascular disease than placebo.

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Publisher

Massachusetts Medical Society

Subject

Administration, Oral

/ Age

/ Aged

/ Aged, 80 and over

/ Aging

/ Aspirin

/ Aspirin - adverse effects