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Health-Status Outcomes with Invasive or Conservative Care in Coronary Disease

by Baloch, Khaula , Mavromichalis, Stavroula , Weintraub, William S , O’Brien, Sean M , Rosenberg, Yves , Alexander, Karen P , Mavromatis, Kreton , Jones, Philip G , Hochman, Judith S , Stone, Gregg W , Newman, Jonathan D , Mark, Daniel B , Cohen, David J , Harrell, Frank E , Boden, William E , Maron, David J , Gosselin, Gilbert , Bangalore, Sripal , Reynolds, Harmony R , Spertus, John A , Diaz, Ariel

in Aged / Angina / Angina pectoris / Angina Pectoris - epidemiology / Bayesian analysis / Cardiovascular disease / Coronary Angiography / Coronary Artery Bypass / Coronary artery disease / Coronary Disease - diagnostic imaging / Coronary Disease - drug therapy / Coronary Disease - surgery / Dyspnea / Female / Health Status / Heart / Heart diseases / Humans / Ischemia / Male / Mathematical models / Medical prognosis / Middle Aged / Myocardial Ischemia - therapy / Myocardial Revascularization - methods / Patients / Probability / Quality of Life / Severity of Illness Index / Statistical analysis / Surveys and Questionnaires / Treatment Outcome

2020

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2020

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2020

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Journal Article

Health-Status Outcomes with Invasive or Conservative Care in Coronary Disease

Baloch, Khaula,

Mavromichalis, Stavroula,

Weintraub, William S,

O’Brien, Sean M,

Rosenberg, Yves,

Alexander, Karen P,

Mavromatis, Kreton,

Jones, Philip G,

Hochman, Judith S,

Stone, Gregg W,

Newman, Jonathan D,

Mark, Daniel B,

Cohen, David J,

Harrell, Frank E,

Boden, William E,

Maron, David J,

Gosselin, Gilbert,

Bangalore, Sripal,

Reynolds, Harmony R,

Spertus, John A,

Diaz, Ariel

2020

Overview

In the ISCHEMIA trial, patients with stable ischemic heart disease were randomly assigned to invasive or conservative treatment. As reported separately, the invasive strategy did not reduce clinical events. Improvements in health status were slightly greater with the invasive strategy, reflecting minimal effects in asymptomatic patients and larger effects in patients with angina symptoms at baseline.

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Publisher

Massachusetts Medical Society

Subject

Aged

/ Angina

/ Angina pectoris

/ Angina Pectoris - epidemiology

/ Bayesian analysis

/ Cardiovascular disease

/ Coronary Angiography