Journal Article

Xylitol Gum and Maternal Transmission of Mutans Streptococci

MURAKAMI YAMANAKA K., NAKAI Y., MORIYA K., SHINGA ISHIHARA C., KAJI M., TAKIMURA M.

2010

Overview

An important caries prevention strategy for children includes measures to interfere with transmission of mutans streptococci (MS). This study confirmed the effectiveness of maternal early exposure to xylitol chewing gum on mother-child transmission of MS. After screening, 107 pregnant women with high salivary MS were randomized into two groups: xylitol gum (Xylitol; n = 56) and no gum (Control; n = 51) groups. Maternal chewing started at the sixth month of pregnancy and terminated 13 months later in the Xylitol group. Outcome measures were the presence of MS in saliva or plaque of the children until age 24 months. The Xylitol-group children were significantly less likely to show MS colonization than Control-group children aged 9–24 months. The Control-group children acquired MS 8.8 months earlier than those in the Xylitol group, suggesting that maternal xylitol gum chewing in Japan shows beneficial effects similar to those demonstrated in Nordic countries.

• Publisher: SAGE Publications,International Association for Dental Research,SAGE PUBLICATIONS, INC
• Subject: Bacterial diseases / Biological and medical sciences / Cariostatic Agents - administration & dosage / Chewing Gum / Chi-Square Distribution / Child, Preschool / Colony Count, Microbial / Dental Caries - microbiology / Dental Caries - prevention & control / Dental Caries Susceptibility - drug effects / Dental Plaque - microbiology / Dental Plaque - prevention & control / Facial bones, jaws, teeth, parodontium: diseases, semeiology / Female / Human bacterial diseases / Humans / Infant / Infectious Disease Transmission, Vertical - prevention & control / Infectious diseases / Longitudinal Studies / Medical sciences / mother-child transmission / Mothers / Mouth - microbiology / mutans streptococci / Non tumoral diseases / Otorhinolaryngology. Stomatology / Pregnancy / Preventive Dentistry / Single-Blind Method / Staphylococcal infections, streptococcal infections, pneumococcal infections / Statistics, Nonparametric / Streptococcal Infections - microbiology / Streptococcal Infections - prevention & control / Streptococcal Infections - transmission / Streptococcus mutans - drug effects / Streptococcus mutans - isolation & purification / Sweetening Agents - administration & dosage / xylitol / Xylitol - administration & dosage