Journal Article

Registry of Transcatheter Aortic-Valve Implantation in High-Risk Patients

Tchetche, Didier, Guyon, Philippe, Boschat, Jacques, Claudel, Jean-Philippe, Sudre, Arnaud, Souteyrand, Geraud, Gommeaux, Antoine, Blanchard, Didier, Iung, Bernard, Leguerrier, Alain, Eltchaninoff, Hélène, Bourlon, Francois, Le Breton, Herve, Collart, Frederic, Bertrand, Bernard, Donzeau-Gouge, Patrick, Favereau, Xavier, Doisy, Vincent, Himbert, Dominique, Grollier, Gilles, Lievre, Michel, Cribier, Alain, Houel, Remi, Teiger, Emmanuel, Lefevre, Thierry, Carrié, Didier, Caussin, Christophe, Tirouvanziam, Ashok, Delpine, Stephane, Prat, Alain, Laskar, Marc, Chevreul, Karine, Albat, Bernard, Collet, Frederic, Leprince, Pascal, Meneveau, Nicolas, Fajadet, Jean, Gilard, Martine, Rioufol, Gilles, Ohlmann, Patrick, Santos, Pierre Dos, Van Belle, Eric

2012

Overview

Data from a French registry of nearly 3200 transcatheter aortic-valve implantation (TAVI) procedures complement data from randomized clinical trials. This emerging technique shows promise in the treatment of high-risk patients with aortic stenosis. Aortic stenosis is now the most frequently diagnosed valvular disease. 1 , 2 Surgical aortic-valve replacement is the definitive therapy for patients with severe symptomatic aortic stenosis. 2 , 3 Operative mortality is low among selected elderly patients but increases with the number and severity of coexisting illnesses. 4 – 6 A survey of hospitalized patients revealed the underreferral to surgery of those with severe symptomatic aortic stenosis. 7 Transcatheter aortic-valve implantation (TAVI) was developed as an alternative to surgical aortic-valve replacement in this high-risk patient population. Ten years after the first implantation by Cribier and colleagues, 8 more than 50,000 patients have been treated by TAVI worldwide. . . .

• Publisher: Massachusetts Medical Society
• Subject: Aged / Aged, 80 and over / Aortic stenosis / Aortic Valve Stenosis / Aortic Valve Stenosis - complications / Aortic Valve Stenosis - therapy / Biological and medical sciences / Cardiac Catheterization / Cardiac Catheterization - methods / Cardiology / Female / France / France - epidemiology / General aspects / Geriatrics / Heart Valve Prosthesis / Heart Valve Prosthesis Implantation / Heart Valve Prosthesis Implantation - adverse effects / Heart Valve Prosthesis Implantation - methods / Hemorrhage / Hemorrhage - epidemiology / Hemorrhage - etiology / Human health and pathology / Humans / Incidence / Life Sciences / Male / Medical sciences / Mortality / Multivariate Analysis / Patients / Prospective Studies / Registries / Regurgitation / Risk groups / Stenosis / Stroke / Stroke - epidemiology / Stroke - etiology / Surgery / Tissues and Organs / Transplants & implants