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Tension-free hernia repair is associated with an increase in inflammatory response markers against the mesh
by
Di Vita, Gaetano
, Milano, Salvatore
, Barbera, Caterina
, Ferlazzo, Viviana
, Cillari, Enrico
, Frazzetta, Michele
, Patti, Rosalia
, Palazzolo, Vincenzo
, Leo, Pietro
in
Abdomen
/ Adult
/ alpha 1-Antitrypsin - metabolism
/ Analgesics
/ Biological and medical sciences
/ Body temperature
/ C-reactive protein
/ C-Reactive Protein - metabolism
/ Ceruloplasmin
/ Complications
/ Cytokines
/ Fibrinogen
/ Fibrinogen - metabolism
/ Foreign-Body Reaction - blood
/ Foreign-Body Reaction - etiology
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Hernia
/ Hernia, Inguinal - immunology
/ Hernia, Inguinal - surgery
/ Hernias
/ Humans
/ Inflammation
/ Inflammation - blood
/ Inflammation - etiology
/ Inflammation - immunology
/ Inflammatory response
/ Interleukin 6
/ Interleukin-6 - blood
/ Interleukins
/ Leukocyte Count
/ Leukocytes
/ Leukocytes (neutrophilic)
/ Male
/ Medical sciences
/ Middle Aged
/ Other diseases. Semiology
/ Pain
/ Patients
/ Polypropylene
/ Polypropylenes - adverse effects
/ Postoperative Complications - blood
/ Postoperative Complications - etiology
/ Postoperative Complications - immunology
/ Postoperative Period
/ Prostheses
/ Prosthesis Implantation - adverse effects
/ Surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgery of the digestive system
/ Surgical mesh
/ Surgical Mesh - adverse effects
/ Transferrin
/ Variance analysis
2000
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Tension-free hernia repair is associated with an increase in inflammatory response markers against the mesh
by
Di Vita, Gaetano
, Milano, Salvatore
, Barbera, Caterina
, Ferlazzo, Viviana
, Cillari, Enrico
, Frazzetta, Michele
, Patti, Rosalia
, Palazzolo, Vincenzo
, Leo, Pietro
in
Abdomen
/ Adult
/ alpha 1-Antitrypsin - metabolism
/ Analgesics
/ Biological and medical sciences
/ Body temperature
/ C-reactive protein
/ C-Reactive Protein - metabolism
/ Ceruloplasmin
/ Complications
/ Cytokines
/ Fibrinogen
/ Fibrinogen - metabolism
/ Foreign-Body Reaction - blood
/ Foreign-Body Reaction - etiology
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Hernia
/ Hernia, Inguinal - immunology
/ Hernia, Inguinal - surgery
/ Hernias
/ Humans
/ Inflammation
/ Inflammation - blood
/ Inflammation - etiology
/ Inflammation - immunology
/ Inflammatory response
/ Interleukin 6
/ Interleukin-6 - blood
/ Interleukins
/ Leukocyte Count
/ Leukocytes
/ Leukocytes (neutrophilic)
/ Male
/ Medical sciences
/ Middle Aged
/ Other diseases. Semiology
/ Pain
/ Patients
/ Polypropylene
/ Polypropylenes - adverse effects
/ Postoperative Complications - blood
/ Postoperative Complications - etiology
/ Postoperative Complications - immunology
/ Postoperative Period
/ Prostheses
/ Prosthesis Implantation - adverse effects
/ Surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgery of the digestive system
/ Surgical mesh
/ Surgical Mesh - adverse effects
/ Transferrin
/ Variance analysis
2000
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Tension-free hernia repair is associated with an increase in inflammatory response markers against the mesh
by
Di Vita, Gaetano
, Milano, Salvatore
, Barbera, Caterina
, Ferlazzo, Viviana
, Cillari, Enrico
, Frazzetta, Michele
, Patti, Rosalia
, Palazzolo, Vincenzo
, Leo, Pietro
in
Abdomen
/ Adult
/ alpha 1-Antitrypsin - metabolism
/ Analgesics
/ Biological and medical sciences
/ Body temperature
/ C-reactive protein
/ C-Reactive Protein - metabolism
/ Ceruloplasmin
/ Complications
/ Cytokines
/ Fibrinogen
/ Fibrinogen - metabolism
/ Foreign-Body Reaction - blood
/ Foreign-Body Reaction - etiology
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Hernia
/ Hernia, Inguinal - immunology
/ Hernia, Inguinal - surgery
/ Hernias
/ Humans
/ Inflammation
/ Inflammation - blood
/ Inflammation - etiology
/ Inflammation - immunology
/ Inflammatory response
/ Interleukin 6
/ Interleukin-6 - blood
/ Interleukins
/ Leukocyte Count
/ Leukocytes
/ Leukocytes (neutrophilic)
/ Male
/ Medical sciences
/ Middle Aged
/ Other diseases. Semiology
/ Pain
/ Patients
/ Polypropylene
/ Polypropylenes - adverse effects
/ Postoperative Complications - blood
/ Postoperative Complications - etiology
/ Postoperative Complications - immunology
/ Postoperative Period
/ Prostheses
/ Prosthesis Implantation - adverse effects
/ Surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgery of the digestive system
/ Surgical mesh
/ Surgical Mesh - adverse effects
/ Transferrin
/ Variance analysis
2000
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Tension-free hernia repair is associated with an increase in inflammatory response markers against the mesh
Journal Article
Tension-free hernia repair is associated with an increase in inflammatory response markers against the mesh
2000
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Overview
Background: The purpose of this study was to evaluate the involvement of inflammatory mediators in patients undergoing Lichtenstein tension-free hernioplasty (LH) using polypropylene prosthetic materials or conventional Bassini hernia repair (BH).
Methods: Thirty patients male with unilateral inguinal hernia without complications or recurrence were included in this study. Randomly, patients underwent LH or BH. Peripheral venous bloods samples were collected 24 hours prior to surgery and then 6, 24, 48 and 168 hours postoperatively.
Results: We present evidences that LH patients showed a higher increased serum level of fibrinogen, C-reactive protein, alpha-1-antitrypsin, and interleukin-6 than BH patients. Postoperative visual analogue scales for pain were reduced on mobilization for patients undergoing LH compared with BH. Neutrophils were significantly increased only in LH compared with baseline. Ceruloplasmin, transferrin, and albumin levels were unmodified after BH or LH.
Conclusions: In conclusion our data show that although LH induces less pain and more rapid postoperative recovery, it is associated with an higher inflammatory response compared with BH, likely due to polypropylene mesh.
Publisher
Elsevier Inc,Elsevier,Elsevier Limited
Subject
/ Adult
/ alpha 1-Antitrypsin - metabolism
/ Biological and medical sciences
/ C-Reactive Protein - metabolism
/ Foreign-Body Reaction - blood
/ Foreign-Body Reaction - etiology
/ Gastroenterology. Liver. Pancreas. Abdomen
/ Hernia
/ Hernia, Inguinal - immunology
/ Hernias
/ Humans
/ Male
/ Pain
/ Patients
/ Polypropylenes - adverse effects
/ Postoperative Complications - blood
/ Postoperative Complications - etiology
/ Postoperative Complications - immunology
/ Prosthesis Implantation - adverse effects
/ Surgery
/ Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
/ Surgery of the digestive system
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