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Unconventional Tissue Engineering Materials in Disguise
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Journal Article
Unconventional Tissue Engineering Materials in Disguise
2020
Overview
Tissue engineering faces a recurring challenge in the transformation of biomaterials into 3D constructs that mimic the biological, chemical, and mechanical features of native tissues. Some of the conventional approaches can be sophisticated and involve extensive material processing and high-cost fabrication procedures. Despite tremendous strides in biomaterials discovery and characterization, the functional and manufacturing limitations have led to the innovation of novel biomimetic techniques that borrow from nature, human-made commodities, and other parts of life to overcome the challenges in tissue engineering and regenerative medicine. This review explores engineering strategies that involve unusual materials for improved functionality, scalability, sustainability, and cost-efficiency. The biomaterials discussed are globally accessible resources and can serve across a wide spectrum of biomedical research areas.
Tissue engineering has demonstrated remarkable progress in facilitating regeneration in diseased or damaged tissues. The field suffers from lack of biomaterials that provide sufficient vascularization for proper integration with surrounding tissues. The development of functional materials can be an efficient approach to address this concern.New strategies involve the rethinking of unconventional materials. Using materials such as plants, paper, ice, textiles, marine organisms, and edible products in modified fabrication techniques also adds the aspect of sustainability in these fields.These approaches address the functional limitations in tissue engineering technologies and offer biological, chemical, and mechanical robustness. With increased utilization of abundant and sustainable resources, the potential of tissue engineering technologies can reach a global scale.
