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Respiratory syncytial virus and influenza hospitalizations in Danish children 2010–2016
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Respiratory syncytial virus and influenza hospitalizations in Danish children 2010–2016
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Respiratory syncytial virus and influenza hospitalizations in Danish children 2010–2016
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Journal Article
Respiratory syncytial virus and influenza hospitalizations in Danish children 2010–2016
2021
Overview
•RSV and influenza infections are frequent causes of child hospitalization.•Influenza immunization is possible; RSV vaccines are tested in phase III trials.•Identification of high-risk groups facilitate influenza/RSV vaccination policies.•Vaccines should be prioritized for children with asthma/chronic disease or siblings.
To pave the way for universal or risk factor-based vaccination strategies, the present study aimed to describe the epidemiology and compare risk factors for hospitalization associated with respiratory syncytial virus (RSV) and influenza virus infections in Danish children.
National register-based cohort study among 403,422 Danish children born 2010–2016.
Prior asthma hospitalization, number of children in the household, chronic disease and maternal history of asthma hospitalization were the most important risk factors for both RSV and influenza hospitalization. The incidence of influenza increased at school start.
Our findings enable targeted vaccination programs for high-risk children with asthma-like disease, chronic disease, siblings in the household, or maternal history of asthma hospitalization.
Publisher
Elsevier Ltd,Elsevier Limited
