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The Spectrum of Serious Infections Among Patients Receiving Immune Checkpoint Blockade for the Treatment of Melanoma
by
Argüello, Esther
, Kyi, Chrisann
, Del Castillo, Maria
, Romero, Fabian A.
, Redelman-Sidi, Gil
, Postow, Michael A.
in
Adolescent
/ Adrenal Cortex Hormones - adverse effects
/ Adrenal Cortex Hormones - therapeutic use
/ Adult
/ Aged
/ Aged, 80 and over
/ Antibodies, Monoclonal - adverse effects
/ Antibodies, Monoclonal - therapeutic use
/ BRIEF REPORTS
/ Cell Cycle Checkpoints
/ Child
/ Child, Preschool
/ Corticoids
/ Female
/ Health risks
/ Humans
/ Immune system
/ Immunologic Factors - administration & dosage
/ Immunologic Factors - therapeutic use
/ Immunotherapy - adverse effects
/ Infection - epidemiology
/ Infection - etiology
/ Infection - microbiology
/ Infection - virology
/ Infliximab - adverse effects
/ Infliximab - therapeutic use
/ Male
/ Medical Records
/ Melanoma
/ Melanoma - complications
/ Melanoma - drug therapy
/ Melanoma - microbiology
/ Middle Aged
/ Molecules
/ Retrospective Studies
/ Risk Factors
/ Spectrum analysis
/ Young Adult
2016
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The Spectrum of Serious Infections Among Patients Receiving Immune Checkpoint Blockade for the Treatment of Melanoma
by
Argüello, Esther
, Kyi, Chrisann
, Del Castillo, Maria
, Romero, Fabian A.
, Redelman-Sidi, Gil
, Postow, Michael A.
in
Adolescent
/ Adrenal Cortex Hormones - adverse effects
/ Adrenal Cortex Hormones - therapeutic use
/ Adult
/ Aged
/ Aged, 80 and over
/ Antibodies, Monoclonal - adverse effects
/ Antibodies, Monoclonal - therapeutic use
/ BRIEF REPORTS
/ Cell Cycle Checkpoints
/ Child
/ Child, Preschool
/ Corticoids
/ Female
/ Health risks
/ Humans
/ Immune system
/ Immunologic Factors - administration & dosage
/ Immunologic Factors - therapeutic use
/ Immunotherapy - adverse effects
/ Infection - epidemiology
/ Infection - etiology
/ Infection - microbiology
/ Infection - virology
/ Infliximab - adverse effects
/ Infliximab - therapeutic use
/ Male
/ Medical Records
/ Melanoma
/ Melanoma - complications
/ Melanoma - drug therapy
/ Melanoma - microbiology
/ Middle Aged
/ Molecules
/ Retrospective Studies
/ Risk Factors
/ Spectrum analysis
/ Young Adult
2016
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The Spectrum of Serious Infections Among Patients Receiving Immune Checkpoint Blockade for the Treatment of Melanoma
by
Argüello, Esther
, Kyi, Chrisann
, Del Castillo, Maria
, Romero, Fabian A.
, Redelman-Sidi, Gil
, Postow, Michael A.
in
Adolescent
/ Adrenal Cortex Hormones - adverse effects
/ Adrenal Cortex Hormones - therapeutic use
/ Adult
/ Aged
/ Aged, 80 and over
/ Antibodies, Monoclonal - adverse effects
/ Antibodies, Monoclonal - therapeutic use
/ BRIEF REPORTS
/ Cell Cycle Checkpoints
/ Child
/ Child, Preschool
/ Corticoids
/ Female
/ Health risks
/ Humans
/ Immune system
/ Immunologic Factors - administration & dosage
/ Immunologic Factors - therapeutic use
/ Immunotherapy - adverse effects
/ Infection - epidemiology
/ Infection - etiology
/ Infection - microbiology
/ Infection - virology
/ Infliximab - adverse effects
/ Infliximab - therapeutic use
/ Male
/ Medical Records
/ Melanoma
/ Melanoma - complications
/ Melanoma - drug therapy
/ Melanoma - microbiology
/ Middle Aged
/ Molecules
/ Retrospective Studies
/ Risk Factors
/ Spectrum analysis
/ Young Adult
2016
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The Spectrum of Serious Infections Among Patients Receiving Immune Checkpoint Blockade for the Treatment of Melanoma
Journal Article
The Spectrum of Serious Infections Among Patients Receiving Immune Checkpoint Blockade for the Treatment of Melanoma
2016
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Overview
The risk of infection among patients receiving immune checkpoint blockade is unknown. We retrospectively reviewed medical records of 740 patients with melanoma who received immune checkpoint blockers. Serious infection occurred in 54 patients (7.3%). The main risk factors were receipt of corticosteroids and/or infliximab.
Publisher
Oxford University Press
Subject
/ Adrenal Cortex Hormones - adverse effects
/ Adrenal Cortex Hormones - therapeutic use
/ Adult
/ Aged
/ Antibodies, Monoclonal - adverse effects
/ Antibodies, Monoclonal - therapeutic use
/ Child
/ Female
/ Humans
/ Immunologic Factors - administration & dosage
/ Immunologic Factors - therapeutic use
/ Immunotherapy - adverse effects
/ Infliximab - adverse effects
/ Infliximab - therapeutic use
/ Male
/ Melanoma
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