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Journal Article
Improved quality of life is the way to longer life
2016
Overview
[...]the physician's and patient's perceptions of toxicity often differ. For this reason, patient-reported outcomes might become the right approach for high-quality assessment of quality of life.8 Thirdly, the definition of the correct endpoint in clinical trials remains essential; progression-free survival is often chosen as a surrogate for overall survival but the two are not always correlated.9,10 In diseases that can have an asymptomatic, slow progressive course, such as advanced renal cell carcinoma, tumour shrinkage might be predictive of treatment efficacy, but this won't necessarily be clinically relevant since tumour shrinkage is not always associated with symptom relief.
Publisher
Elsevier Ltd,Elsevier Limited
