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Oral Prednisolone for Preschool Children with Acute Virus-Induced Wheezing
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Oral Prednisolone for Preschool Children with Acute Virus-Induced Wheezing
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Journal Article
Oral Prednisolone for Preschool Children with Acute Virus-Induced Wheezing
2009
Overview
Wheezing is common among preschool children with an upper respiratory infection even when they do not have a clear predisposition to asthma. In this study, no benefit in the duration of in-hospital treatment was noted among children who received oral prednisolone, as compared with placebo; all children were treated with inhaled albuterol.
No benefit in the duration of in-hospital treatment was noted among children who received oral prednisolone, as compared with placebo; all children were treated with inhaled albuterol.
Attacks of wheezing that are induced by viral infections of the upper respiratory tract are common in children under the age of 6 years.
1
,
2
The majority of preschool children with virus-triggered wheezing have few or no interval respiratory symptoms and no chronic lower airway eosinophilia.
2
–
5
Furthermore, the propensity to wheeze with upper respiratory viral infections often resolves by school age.
6
,
7
National guidelines, which are based on the efficacy of systemic corticosteroids in reducing the duration of hospitalization in school-age children and adults with classic atopic asthma,
8
–
10
recommend the use of oral corticosteroids for preschool children with . . .
Publisher
Massachusetts Medical Society
Subject
/ Age
/ Biological and medical sciences
/ Bronchodilator Agents - therapeutic use
/ Child
/ Chronic obstructive pulmonary disease, asthma
/ Female
/ Glucocorticoids - adverse effects
/ Glucocorticoids - therapeutic use
/ Hospitalization - statistics & numerical data
/ Humans
/ Infant
/ Male
/ Prednisolone - adverse effects
/ Prednisolone - therapeutic use
/ Respiratory Sounds - drug effects
/ Respiratory Sounds - etiology
/ Respiratory Tract Infections - complications
