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Study protocol for a randomized controlled trial assessing the effect of lateral position intubation on bronchial blocker placement during unilateral video-assisted thoracic surgery
by
Zhou, Bei
, Tong, Fei
, Hu, Siping
, Liu, He
, Hu, Yonghe
, Tan, Huijuan
, Liu, Xi
, Zhang, Xi
, Zhang, Zhengduo
, Tang, Yawen
, Liu, Feifan
in
Adolescent
/ Adult
/ Aged
/ Aged, 80 and over
/ Airway management
/ Anesthesia
/ Anesthesia, General
/ Anesthesiology
/ Biomedicine
/ Blood pressure
/ Bronchial blocker
/ Bronchoscopy
/ Clinical medicine
/ Clinical trials
/ Data collection
/ Equivalence Trials as Topic
/ Female
/ Fiber Optic Technology
/ General anesthesia
/ Health Sciences
/ Hospital patients
/ Hospitals
/ Humans
/ Hypoxemia
/ Informed consent
/ Intratracheal intubation
/ Intubation
/ Intubation, Intratracheal - adverse effects
/ Intubation, Intratracheal - instrumentation
/ Intubation, Intratracheal - methods
/ Lateral position
/ Male
/ Malposition
/ Medical personnel
/ Medicine
/ Medicine & Public Health
/ Middle Aged
/ Patient compliance
/ Patient Positioning - methods
/ Patients
/ Postoperative period
/ Randomized Controlled Trials as Topic
/ Recovery (Medical)
/ Remifentanil
/ Statistics for Life Sciences
/ Study Protocol
/ Sufentanil
/ Surgery
/ Thoracic surgery
/ Thoracic Surgery, Video-Assisted - adverse effects
/ Thoracic Surgery, Video-Assisted - methods
/ Time Factors
/ Treatment Outcome
/ Video-assisted thoracic surgery
/ Vital signs
/ Young Adult
2025
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Study protocol for a randomized controlled trial assessing the effect of lateral position intubation on bronchial blocker placement during unilateral video-assisted thoracic surgery
by
Zhou, Bei
, Tong, Fei
, Hu, Siping
, Liu, He
, Hu, Yonghe
, Tan, Huijuan
, Liu, Xi
, Zhang, Xi
, Zhang, Zhengduo
, Tang, Yawen
, Liu, Feifan
in
Adolescent
/ Adult
/ Aged
/ Aged, 80 and over
/ Airway management
/ Anesthesia
/ Anesthesia, General
/ Anesthesiology
/ Biomedicine
/ Blood pressure
/ Bronchial blocker
/ Bronchoscopy
/ Clinical medicine
/ Clinical trials
/ Data collection
/ Equivalence Trials as Topic
/ Female
/ Fiber Optic Technology
/ General anesthesia
/ Health Sciences
/ Hospital patients
/ Hospitals
/ Humans
/ Hypoxemia
/ Informed consent
/ Intratracheal intubation
/ Intubation
/ Intubation, Intratracheal - adverse effects
/ Intubation, Intratracheal - instrumentation
/ Intubation, Intratracheal - methods
/ Lateral position
/ Male
/ Malposition
/ Medical personnel
/ Medicine
/ Medicine & Public Health
/ Middle Aged
/ Patient compliance
/ Patient Positioning - methods
/ Patients
/ Postoperative period
/ Randomized Controlled Trials as Topic
/ Recovery (Medical)
/ Remifentanil
/ Statistics for Life Sciences
/ Study Protocol
/ Sufentanil
/ Surgery
/ Thoracic surgery
/ Thoracic Surgery, Video-Assisted - adverse effects
/ Thoracic Surgery, Video-Assisted - methods
/ Time Factors
/ Treatment Outcome
/ Video-assisted thoracic surgery
/ Vital signs
/ Young Adult
2025
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Study protocol for a randomized controlled trial assessing the effect of lateral position intubation on bronchial blocker placement during unilateral video-assisted thoracic surgery
by
Zhou, Bei
, Tong, Fei
, Hu, Siping
, Liu, He
, Hu, Yonghe
, Tan, Huijuan
, Liu, Xi
, Zhang, Xi
, Zhang, Zhengduo
, Tang, Yawen
, Liu, Feifan
in
Adolescent
/ Adult
/ Aged
/ Aged, 80 and over
/ Airway management
/ Anesthesia
/ Anesthesia, General
/ Anesthesiology
/ Biomedicine
/ Blood pressure
/ Bronchial blocker
/ Bronchoscopy
/ Clinical medicine
/ Clinical trials
/ Data collection
/ Equivalence Trials as Topic
/ Female
/ Fiber Optic Technology
/ General anesthesia
/ Health Sciences
/ Hospital patients
/ Hospitals
/ Humans
/ Hypoxemia
/ Informed consent
/ Intratracheal intubation
/ Intubation
/ Intubation, Intratracheal - adverse effects
/ Intubation, Intratracheal - instrumentation
/ Intubation, Intratracheal - methods
/ Lateral position
/ Male
/ Malposition
/ Medical personnel
/ Medicine
/ Medicine & Public Health
/ Middle Aged
/ Patient compliance
/ Patient Positioning - methods
/ Patients
/ Postoperative period
/ Randomized Controlled Trials as Topic
/ Recovery (Medical)
/ Remifentanil
/ Statistics for Life Sciences
/ Study Protocol
/ Sufentanil
/ Surgery
/ Thoracic surgery
/ Thoracic Surgery, Video-Assisted - adverse effects
/ Thoracic Surgery, Video-Assisted - methods
/ Time Factors
/ Treatment Outcome
/ Video-assisted thoracic surgery
/ Vital signs
/ Young Adult
2025
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Study protocol for a randomized controlled trial assessing the effect of lateral position intubation on bronchial blocker placement during unilateral video-assisted thoracic surgery
Journal Article
Study protocol for a randomized controlled trial assessing the effect of lateral position intubation on bronchial blocker placement during unilateral video-assisted thoracic surgery
2025
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Overview
Background
Approximately one-third of patients who undergo bronchial blocker (BB) intubation in the conventional supine position suffer BB malposition. This trial aims to explore the efficiency and clinical application of BB intubation in the lateral position to reduce the incidence of BB malposition in patients undergoing video-assisted thoracic surgery (VATS).
Methods
This single-center, parallel-group, randomized controlled trial will enroll 110 patients aged 18–80 years who are scheduled for elective unilateral VATS with BB intubation under general anesthesia. Participants will be randomly assigned (1:1) to either the lateral BB intubation group or the conventional supine BB intubation group. The primary outcome is the incidence of BB malposition observed by fiberoptic bronchoscopy (FOB). Secondary outcomes include the duration of intubation, the frequency and duration of FOB usage, whether to re-intubate, intraoperative vital signs, and postoperative recovery.
Discussion
This trial will confirm the clinical efficacy and superiority of BB intubation in the lateral position to consolidate the lateral intubation pattern in thoracic anesthesia. We expect that performing lateral BB intubation can reduce the BB malposition rate and result in more stable intraoperative vital signs and fewer postoperative complications, which is in line with the concept of Enhanced Recovery After Surgery in thoracic anesthesia.
Trial registration
Chinese Clinical Trial Registry ChiCTR2400081961. Registered on March 18, 2024.
Publisher
BioMed Central,BioMed Central Ltd,Springer Nature B.V,BMC
Subject
/ Adult
/ Aged
/ Female
/ Humans
/ Intubation, Intratracheal - adverse effects
/ Intubation, Intratracheal - instrumentation
/ Intubation, Intratracheal - methods
/ Male
/ Medicine
/ Patient Positioning - methods
/ Patients
/ Randomized Controlled Trials as Topic
/ Statistics for Life Sciences
/ Surgery
/ Thoracic Surgery, Video-Assisted - adverse effects
/ Thoracic Surgery, Video-Assisted - methods
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