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Isotope-dilution mass spectrometry for exact quantification of noncanonical DNA nucleosides
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Isotope-dilution mass spectrometry for exact quantification of noncanonical DNA nucleosides
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Journal Article
Isotope-dilution mass spectrometry for exact quantification of noncanonical DNA nucleosides
2019
Overview
In addition to canonical nucleotides, DNA contains various modified bases that contribute to the developmental and disease state of the organism. UHPLC–MS/MS with isotopically labeled standards is used in this protocol to quantify modified bases.
Publisher
Nature Publishing Group
Subject
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