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Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

by Andrews, Nick , Zambon, Maria , Stowe, Julia , Chand, Meera , Tessier, Elise , Amirthalingam, Gayatri , Lopez Bernal, Jamie , Brown, Kevin E , Myers, Richard , Ramsay, Mary , Thelwall, Simon , Edmunds, Matt , Gower, Charlotte , Dabrera, Gavin , Groves, Natalie , Campbell, Colin N.J , Hopkins, Susan , Gallagher, Eileen , Simmons, Ruth

in Adolescent / Adult / Aged / Aged, 80 and over / Case-Control Studies / Coronavirus / Coronaviruses / COVID-19 / COVID-19 - epidemiology / COVID-19 - prevention & control / COVID-19 - virology / COVID-19 vaccines / COVID-19 Vaccines - immunology / Female / Humans / Immunization / Immunogenicity, Vaccine / Infectious Disease / Laboratories / Male / Middle Aged / Original / Public health / SARS-CoV-2 / Severe acute respiratory syndrome coronavirus 2 / Treatment Outcome / United Kingdom - epidemiology / Vaccine efficacy / Vaccine Potency / Vaccines / Young Adult

2021

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Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

2021

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Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

2021

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Journal Article

Effectiveness of Covid-19 Vaccines against the B.1.617.2 (Delta) Variant

Andrews, Nick,

Zambon, Maria,

Stowe, Julia,

Chand, Meera,

Tessier, Elise,

Amirthalingam, Gayatri,

Lopez Bernal, Jamie,

Brown, Kevin E,

Myers, Richard,

Ramsay, Mary,

Thelwall, Simon,

Edmunds, Matt,

Gower, Charlotte,

Dabrera, Gavin,

Groves, Natalie,

Campbell, Colin N.J,

Hopkins, Susan,

Gallagher, Eileen,

Simmons, Ruth

2021

Overview

The B.1.617.2 (delta) Covid-19 variant has surged in India and spread worldwide. In a test-negative case–control study, the effectiveness of two doses of BNT162b2 was 94% against the B.1.1.7 (alpha) variant and 88% against delta; with the ChAdOx1 nCoV-19 vaccine, effectiveness was 74% and 67%, respectively. Protection after a single vaccine injection was low; two doses are needed.

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Publisher

Massachusetts Medical Society

Subject

Adolescent

/ Adult

/ Aged

/ Aged, 80 and over

/ Case-Control Studies

/ Coronavirus

/ Coronaviruses