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BNT162b2 Protection against the Omicron Variant in Children and Adolescents

by Schuster, Jennifer E. , Pannaraj, Pia S. , Gertz, Shira J. , Irby, Katherine , Chatani, Brandon M. , Schwartz, Stephanie P. , Chiotos, Kathleen , Tarquinio, Keiko M. , Typpo, Katri V. , Cvijanovich, Natalie Z. , Nofziger, Ryan A. , Hume, Janet R. , Kamidani, Satoshi , Tenforde, Mark W. , Cullimore, Melissa L. , Randolph, Adrienne G. , Halasa, Natasha B. , Maddux, Aline B. , Levy, Emily R. , Flori, Heidi R. , Patel, Manish M. , Mack, Elizabeth H. , Olson, Samantha M. , Newhams, Margaret M. , Bhumbra, Samina S. , Hobbs, Charlotte V. , Boom, Julie A. , Coates, Bria M. , Zinter, Matt S. , Walker, Tracie C. , Heidemann, Sabrina M. , Smallcomb, Laura , Campbell, Angela P. , Maamari, Mia , Price, Ashley M. , Kong, Michele , Staat, Mary A. , Bline, Katherine E. , Bradford, Tamara T. , Cameron, Melissa A. , Sahni, Leila C. , Zambrano, Laura D.

in Adolescence / Adolescent / Adolescent Medicine / Adolescents / Age / Age groups / Antigens / BNT162 Vaccine - therapeutic use / Case-Control Studies / Child / Child, Preschool / Children / Coronavirus / Coronaviruses / COVID-19 / COVID-19 - prevention & control / COVID-19 vaccines / COVID-19 Vaccines - therapeutic use / Critical Illness - therapy / Electronic health records / Hospitalization / Hospitals / Humans / Illnesses / Immunization / Infectious Disease / Medical records / mRNA / mRNA Vaccines - therapeutic use / Original / Patients / Pediatrics / Pediatrics General / SARS-CoV-2 / Severe acute respiratory syndrome coronavirus 2 / Surveillance / Teenagers / Vaccine Efficacy / Vaccines / Vaccines, Synthetic - therapeutic use / Viral Infections

2022

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BNT162b2 Protection against the Omicron Variant in Children and Adolescents

2022

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2022

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Journal Article

BNT162b2 Protection against the Omicron Variant in Children and Adolescents

Schuster, Jennifer E.,

Pannaraj, Pia S.,

Gertz, Shira J.,

Irby, Katherine,

Chatani, Brandon M.,

Schwartz, Stephanie P.,

Chiotos, Kathleen,

Tarquinio, Keiko M.,

Typpo, Katri V.,

Cvijanovich, Natalie Z.,

Nofziger, Ryan A.,

Hume, Janet R.,

Kamidani, Satoshi,

Tenforde, Mark W.,

Cullimore, Melissa L.,

Randolph, Adrienne G.,

Halasa, Natasha B.,

Maddux, Aline B.,

Levy, Emily R.,

Flori, Heidi R.,

Patel, Manish M.,

Mack, Elizabeth H.,

Olson, Samantha M.,

Newhams, Margaret M.,

Bhumbra, Samina S.,

Hobbs, Charlotte V.,

Boom, Julie A.,

Coates, Bria M.,

Zinter, Matt S.,

Walker, Tracie C.,

Heidemann, Sabrina M.,

Smallcomb, Laura,

Campbell, Angela P.,

Maamari, Mia,

Price, Ashley M.,

Kong, Michele,

Staat, Mary A.,

Bline, Katherine E.,

Bradford, Tamara T.,

Cameron, Melissa A.,

Sahni, Leila C.,

Zambrano, Laura D.

2022

Overview

In this study evaluating BNT162b2, vaccine effectiveness against hospitalization for Covid-19 in the delta-predominant period among adolescents 12 to 18 years of age was more than 90%; during the omicron period, vaccine effectiveness was 40% against hospitalization and 79% against critical illness. Vaccine effectiveness against hospitalization was 68% among children 5 to 11 years of age.

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Publisher

Massachusetts Medical Society

Subject

Adolescence

/ Adolescent

/ Adolescent Medicine

/ Adolescents

/ Age

/ Age groups

/ Antigens