Asset Details
Do you wish to reserve the book?
Genomic characterization of highly pathogenic avian influenza A H5N1 virus newly emerged in dairy cattle
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Genomic characterization of highly pathogenic avian influenza A H5N1 virus newly emerged in dairy cattle
Do you wish to request the book?
Genomic characterization of highly pathogenic avian influenza A H5N1 virus newly emerged in dairy cattle
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Genomic characterization of highly pathogenic avian influenza A H5N1 virus newly emerged in dairy cattle
2024
Overview
In March 2024, the emergence of highly pathogenic avian influenza (HPAI) A (H5N1) infections in dairy cattle was detected in the United Sates for the first time. We genetically characterize HPAI viruses from dairy cattle showing an abrupt drop in milk production, as well as from two cats, six wild birds, and one skunk. They share nearly identical genome sequences, forming a new genotype B3.13 within the 2.3.4.4b clade. B3.13 viruses underwent two reassortment events since 2023 and exhibit critical mutations in HA, M1, and NS genes but lack critical mutations in PB2 and PB1 genes, which enhance virulence or adaptation to mammals. The PB2 E627 K mutation in a human case associated with cattle underscores the potential for rapid evolution post infection, highlighting the need for continued surveillance to monitor public health threats.
Publisher
Taylor & Francis Ltd,Taylor & Francis,Taylor & Francis Group
Subject
/ Cattle
/ Emerging Seasonal and Pandemic Influenza Infections
/ Genomes
/ Genotype
/ H5N1
/ Highly pathogenic avian influenza (HPAI)
/ Humans
/ Influenza A Virus, H5N1 Subtype - classification
/ Influenza A Virus, H5N1 Subtype - genetics
/ Influenza A Virus, H5N1 Subtype - isolation & purification
/ Influenza A Virus, H5N1 Subtype - pathogenicity
/ Influenza in Birds - virology
/ Mutation
/ Orthomyxoviridae Infections - veterinary
/ Orthomyxoviridae Infections - virology
/ Reassortant Viruses - classification
/ Reassortant Viruses - genetics
/ Reassortant Viruses - isolation & purification
/ Reassortant Viruses - pathogenicity
/ Viruses
