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Towards a youth mental health paradigm: a perspective and roadmap

by Meyer-Lindenberg, Andreas , Allen, Nicholas B. , Chanen, Andrew , Reininghaus, Ulrich , Patton, George C. , Woo, T. Wilson , Lee, Francis S. , Wood, Stephen J. , Davey, Christopher G. , Srihari, Vinod H. , Uhlhaas, Peter J. , Fisher, Helen L. , Verma, Swapna K. , Bella-Awusah, Tolulope , Liu, Cindy H. , Keshavan, Matcheri S. , Frangou, Sophia , Mehta, Urvakhsh Meherwan , Konrad, Kerstin , McGorry, Patrick D. , Yung, Alison R. , Luna, Beatriz , Avenevoli, Shelli , Chen, Eric Y. H. , Öngür, Dost , Sawa, Akira , Schumann, Gunter , Correll, Christoph U. , Torous, John , Nordentoft, Merete , Hickie, Ian B. , Do, Kim Q. , Paus, Tomáš , Susser, Ezra , Shah, Jai , Yang, Lawrence H. , Schoenbaum, Michael

in 692/53/2421 / 692/699/476 / Adolescent / Behavioral Sciences / Biological Psychology / Bipolar disorder / Diagnosis / Humans / Intervention / Medicine / Medicine & Public Health / Mental disorders / Mental Disorders - diagnosis / Mental Disorders - therapy / Mental Health / Neurosciences / Perspective / Pharmacotherapy / Psychiatry / Psychopathology

2023

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2023

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2023

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Journal Article

Towards a youth mental health paradigm: a perspective and roadmap

Meyer-Lindenberg, Andreas,

Allen, Nicholas B.,

Chanen, Andrew,

Reininghaus, Ulrich,

Patton, George C.,

Woo, T. Wilson,

Lee, Francis S.,

Wood, Stephen J.,

Davey, Christopher G.,

Srihari, Vinod H.,

Uhlhaas, Peter J.,

Fisher, Helen L.,

Verma, Swapna K.,

Bella-Awusah, Tolulope,

Liu, Cindy H.,

Keshavan, Matcheri S.,

Frangou, Sophia,

Mehta, Urvakhsh Meherwan,

Konrad, Kerstin,

McGorry, Patrick D.,

Yung, Alison R.,

Luna, Beatriz,

Avenevoli, Shelli,

Chen, Eric Y. H.,

Öngür, Dost,

Sawa, Akira,

Schumann, Gunter,

Correll, Christoph U.,

Torous, John,

Nordentoft, Merete,

Hickie, Ian B.,

Do, Kim Q.,

Paus, Tomáš,

Susser, Ezra,

Shah, Jai,

Yang, Lawrence H.,

Schoenbaum, Michael

2023

Overview

Most mental disorders have a typical onset between 12 and 25 years of age, highlighting the importance of this period for the pathogenesis, diagnosis, and treatment of mental ill-health. This perspective addresses interactions between risk and protective factors and brain development as key pillars accounting for the emergence of psychopathology in youth. Moreover, we propose that novel approaches towards early diagnosis and interventions are required that reflect the evolution of emerging psychopathology, the importance of novel service models, and knowledge exchange between science and practitioners. Taken together, we propose a transformative early intervention paradigm for research and clinical care that could significantly enhance mental health in young people and initiate a shift towards the prevention of severe mental disorders.

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Publisher

Nature Publishing Group UK,Nature Publishing Group

Subject

692/53/2421

/ 692/699/476

/ Adolescent

/ Behavioral Sciences

/ Biological Psychology

/ Bipolar disorder

/ Diagnosis