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A Comparative Evaluation of EUS-Guided Biliary Drainage and Percutaneous Drainage in Patients with Distal Malignant Biliary Obstruction and Failed ERCP
by
Lennon, Anne Marie
, Singh, Vikesh K.
, Valeshabad, Ali Kord
, Saxena, Payal
, Khashab, Mouen A.
, Afghani, Elham
, Messallam, Ahmed
, Kumbhari, Vivek
, Canto, Marcia Irene
, Kalloo, Anthony N.
, El Zein, Mohamad
in
Aged
/ Biochemistry
/ Cholangiopancreatography, Endoscopic Retrograde
/ Cholestasis - diagnosis
/ Cholestasis - etiology
/ Cholestasis - therapy
/ Cost-Benefit Analysis
/ Drainage - adverse effects
/ Drainage - economics
/ Drainage - methods
/ Endoscopic retrograde cholangiopancreatography
/ Endosonography - adverse effects
/ Endosonography - economics
/ Female
/ Gastroenterology
/ Health Care Costs
/ Hepatology
/ Humans
/ Jaundice, Obstructive - diagnosis
/ Jaundice, Obstructive - etiology
/ Jaundice, Obstructive - therapy
/ Male
/ Medicine
/ Medicine & Public Health
/ Middle Aged
/ Neoplasms - complications
/ Oncology
/ Original Article
/ Pneumoviridae
/ Retreatment
/ Retrospective Studies
/ Transplant Surgery
/ Treatment Failure
/ Ultrasonography, Interventional - adverse effects
/ Ultrasonography, Interventional - economics
2015
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A Comparative Evaluation of EUS-Guided Biliary Drainage and Percutaneous Drainage in Patients with Distal Malignant Biliary Obstruction and Failed ERCP
by
Lennon, Anne Marie
, Singh, Vikesh K.
, Valeshabad, Ali Kord
, Saxena, Payal
, Khashab, Mouen A.
, Afghani, Elham
, Messallam, Ahmed
, Kumbhari, Vivek
, Canto, Marcia Irene
, Kalloo, Anthony N.
, El Zein, Mohamad
in
Aged
/ Biochemistry
/ Cholangiopancreatography, Endoscopic Retrograde
/ Cholestasis - diagnosis
/ Cholestasis - etiology
/ Cholestasis - therapy
/ Cost-Benefit Analysis
/ Drainage - adverse effects
/ Drainage - economics
/ Drainage - methods
/ Endoscopic retrograde cholangiopancreatography
/ Endosonography - adverse effects
/ Endosonography - economics
/ Female
/ Gastroenterology
/ Health Care Costs
/ Hepatology
/ Humans
/ Jaundice, Obstructive - diagnosis
/ Jaundice, Obstructive - etiology
/ Jaundice, Obstructive - therapy
/ Male
/ Medicine
/ Medicine & Public Health
/ Middle Aged
/ Neoplasms - complications
/ Oncology
/ Original Article
/ Pneumoviridae
/ Retreatment
/ Retrospective Studies
/ Transplant Surgery
/ Treatment Failure
/ Ultrasonography, Interventional - adverse effects
/ Ultrasonography, Interventional - economics
2015
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A Comparative Evaluation of EUS-Guided Biliary Drainage and Percutaneous Drainage in Patients with Distal Malignant Biliary Obstruction and Failed ERCP
by
Lennon, Anne Marie
, Singh, Vikesh K.
, Valeshabad, Ali Kord
, Saxena, Payal
, Khashab, Mouen A.
, Afghani, Elham
, Messallam, Ahmed
, Kumbhari, Vivek
, Canto, Marcia Irene
, Kalloo, Anthony N.
, El Zein, Mohamad
in
Aged
/ Biochemistry
/ Cholangiopancreatography, Endoscopic Retrograde
/ Cholestasis - diagnosis
/ Cholestasis - etiology
/ Cholestasis - therapy
/ Cost-Benefit Analysis
/ Drainage - adverse effects
/ Drainage - economics
/ Drainage - methods
/ Endoscopic retrograde cholangiopancreatography
/ Endosonography - adverse effects
/ Endosonography - economics
/ Female
/ Gastroenterology
/ Health Care Costs
/ Hepatology
/ Humans
/ Jaundice, Obstructive - diagnosis
/ Jaundice, Obstructive - etiology
/ Jaundice, Obstructive - therapy
/ Male
/ Medicine
/ Medicine & Public Health
/ Middle Aged
/ Neoplasms - complications
/ Oncology
/ Original Article
/ Pneumoviridae
/ Retreatment
/ Retrospective Studies
/ Transplant Surgery
/ Treatment Failure
/ Ultrasonography, Interventional - adverse effects
/ Ultrasonography, Interventional - economics
2015
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A Comparative Evaluation of EUS-Guided Biliary Drainage and Percutaneous Drainage in Patients with Distal Malignant Biliary Obstruction and Failed ERCP
Journal Article
A Comparative Evaluation of EUS-Guided Biliary Drainage and Percutaneous Drainage in Patients with Distal Malignant Biliary Obstruction and Failed ERCP
2015
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Overview
Background and Aim
Endoscopic ultrasound-guided biliary drainage (EGBD) may be a safe, alternative technique to percutaneous transhepatic biliary drainage (PTBD) in patients who fail ERCP. However, it is currently unknown how both techniques compare in terms of efficacy, safety, and cost. The aims of this study were to compare efficacy, safety, and cost of EGBD to that of PTBD.
Methods
Jaundiced patients with distal malignant biliary obstruction who underwent EGBD or PTBD after failed ERCP were included. Technical success, clinical success, and adverse events between the two groups were compared.
Results
A total of 73 patients with failed ERCP subsequently underwent EGBD (
n
= 22) or PTBD (
n
= 51). Although technical success was higher in the PTBD group (100 vs. 86.4 %,
p
= 0.007), clinical success was equivalent (92.2 vs. 86.4 %,
p
= 0.40). PTBD was associated with higher adverse event rate (index procedure: 39.2 vs. 18.2 %; all procedures including reinterventions: 80.4 vs. 15.7 %). Stent patency and survival were equivalent between both groups. Total charges were more than two times higher in the PTBD group (
p
= 0.004) mainly due to significantly higher rate of reinterventions (80.4 vs. 15.7 %,
p
< 0.001).
Conclusion
EGBD and PTBD are comparably effective techniques for treatment of distal malignant biliary obstruction after failed ERCP. However, EGBD is associated with decreased adverse events rate and is significantly less costly due to the need for fewer reinterventions. Our results suggest that EGBD should be the technique of choice for treatment of these patients at institutions with experienced interventional endosonographers.
Publisher
Springer US,Springer,Springer Nature B.V
Subject
/ Cholangiopancreatography, Endoscopic Retrograde
/ Endoscopic retrograde cholangiopancreatography
/ Endosonography - adverse effects
/ Female
/ Humans
/ Jaundice, Obstructive - diagnosis
/ Jaundice, Obstructive - etiology
/ Jaundice, Obstructive - therapy
/ Male
/ Medicine
/ Oncology
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