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Mother-to-Child Transmission of HTLV-1 Epidemiological Aspects, Mechanisms and Determinants of Mother-to-Child Transmission
by
Gessain, Antoine
, Percher, Florent
, Jeannin, Patricia
, Martin-Latil, Sandra
, Vidy-Roche, Aurore
, Afonso, Philippe
, Ceccaldi, Pierre-Emmanuel
in
Acute Disease
/ Adult
/ Anemia, Hemolytic
/ breastfeeding
/ Female
/ HTLV-1
/ HTLV-I Infections - epidemiology
/ HTLV-I Infections - transmission
/ HTLV-I Infections - virology
/ human
/ Human T-lymphotropic virus 1 - genetics
/ Human T-lymphotropic virus 1 - physiology
/ Humans
/ Infant
/ Infectious Disease Transmission, Vertical
/ Infectious Mononucleosis
/ intestinal barrier
/ Life Sciences
/ Male
/ Microbiology and Parasitology
/ Middle Aged
/ retrovirus
/ Review
/ Virology
2016
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Mother-to-Child Transmission of HTLV-1 Epidemiological Aspects, Mechanisms and Determinants of Mother-to-Child Transmission
by
Gessain, Antoine
, Percher, Florent
, Jeannin, Patricia
, Martin-Latil, Sandra
, Vidy-Roche, Aurore
, Afonso, Philippe
, Ceccaldi, Pierre-Emmanuel
in
Acute Disease
/ Adult
/ Anemia, Hemolytic
/ breastfeeding
/ Female
/ HTLV-1
/ HTLV-I Infections - epidemiology
/ HTLV-I Infections - transmission
/ HTLV-I Infections - virology
/ human
/ Human T-lymphotropic virus 1 - genetics
/ Human T-lymphotropic virus 1 - physiology
/ Humans
/ Infant
/ Infectious Disease Transmission, Vertical
/ Infectious Mononucleosis
/ intestinal barrier
/ Life Sciences
/ Male
/ Microbiology and Parasitology
/ Middle Aged
/ retrovirus
/ Review
/ Virology
2016
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Mother-to-Child Transmission of HTLV-1 Epidemiological Aspects, Mechanisms and Determinants of Mother-to-Child Transmission
by
Gessain, Antoine
, Percher, Florent
, Jeannin, Patricia
, Martin-Latil, Sandra
, Vidy-Roche, Aurore
, Afonso, Philippe
, Ceccaldi, Pierre-Emmanuel
in
Acute Disease
/ Adult
/ Anemia, Hemolytic
/ breastfeeding
/ Female
/ HTLV-1
/ HTLV-I Infections - epidemiology
/ HTLV-I Infections - transmission
/ HTLV-I Infections - virology
/ human
/ Human T-lymphotropic virus 1 - genetics
/ Human T-lymphotropic virus 1 - physiology
/ Humans
/ Infant
/ Infectious Disease Transmission, Vertical
/ Infectious Mononucleosis
/ intestinal barrier
/ Life Sciences
/ Male
/ Microbiology and Parasitology
/ Middle Aged
/ retrovirus
/ Review
/ Virology
2016
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Mother-to-Child Transmission of HTLV-1 Epidemiological Aspects, Mechanisms and Determinants of Mother-to-Child Transmission
Journal Article
Mother-to-Child Transmission of HTLV-1 Epidemiological Aspects, Mechanisms and Determinants of Mother-to-Child Transmission
2016
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Overview
Human T-cell Lymphotropic Virus type 1 (HTLV-1) is a human retrovirus that infects at least 5–10 million people worldwide, and is the etiological agent of a lymphoproliferative malignancy; Adult T-cell Leukemia/Lymphoma (ATLL); and a chronic neuromyelopathy, HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP), as well as other inflammatory diseases such as infective dermatitis and uveitis. Besides sexual intercourse and intravenous transmission, HTLV-1 can also be transmitted from infected mother to child during prolonged breastfeeding. Some characteristics that are linked to mother-to-child transmission (MTCT) of HTLV-1, such as the role of proviral load, antibody titer of the infected mother, and duration of breastfeeding, have been elucidated; however, most of the mechanisms underlying HTLV-1 transmission during breast feeding remain largely unknown, such as the sites of infection and cellular targets as well as the role of milk factors. The present review focuses on the latest findings and current opinions and perspectives on MTCT of HTLV-1.
Publisher
MDPI,MDPI AG
Subject
/ Adult
/ Female
/ HTLV-1
/ HTLV-I Infections - epidemiology
/ HTLV-I Infections - transmission
/ HTLV-I Infections - virology
/ human
/ Human T-lymphotropic virus 1 - genetics
/ Human T-lymphotropic virus 1 - physiology
/ Humans
/ Infant
/ Infectious Disease Transmission, Vertical
/ Male
/ Microbiology and Parasitology
/ Review
/ Virology
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