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Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer

by Geyer, Charles E , Fleming, Gini F , Coates, Alan S , Climent, Miguel A , Coleman, Robert , Debled, Marc , Buchholz, Stefan , Pavesi, Lorenzo , Ruhstaller, Thomas , Stearns, Vered , Láng, István , Di Leo, Angelo , Puglisi, Fabio , Spazzapan, Simon , Colleoni, Marco , Francis, Prudence A , Burstein, Harold J , Gómez, Henry L , Bonnefoi, Hervé R , Tondini, Carlo , Maibach, Rudolf , Goldhirsch, Aron , Davidson, Nancy E , Rabaglio-Poretti, Manuela , Regan, Meredith M , Ingle, James N , Bellet, Meritxell , Goetz, Matthew P , Martino, Silvana , Pinotti, Graziella , Ciruelos, Eva , Winer, Eric P , Gelber, Richard D , Ruepp, Barbara , Walley, Barbara A , Pagani, Olivia

in Adjuvants / Adult / Androstadienes - adverse effects / Androstadienes - therapeutic use / Antineoplastic Agents, Hormonal - adverse effects / Antineoplastic Agents, Hormonal - therapeutic use / Aromatase / Aromatase Inhibitors - adverse effects / Aromatase Inhibitors - therapeutic use / Breast cancer / Breast Neoplasms - drug therapy / Breast Neoplasms - surgery / Cancer therapies / Chemotherapy / Chemotherapy, Adjuvant / Design / Disease-Free Survival / Drug dosages / Endocrine therapy / ErbB-2 protein / Female / Follow-Up Studies / Hospitals / Humans / Kaplan-Meier Estimate / Medical research / Middle Aged / Neoplasm Recurrence, Local - prevention & control / Oncology / Premenopause / Receptor, ErbB-2 / Survival / Tamoxifen / Tamoxifen - adverse effects / Tamoxifen - therapeutic use / Womens health / Young Adult

2018

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Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer

2018

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2018

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Journal Article

Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer

Geyer, Charles E,

Fleming, Gini F,

Coates, Alan S,

Climent, Miguel A,

Coleman, Robert,

Debled, Marc,

Buchholz, Stefan,

Pavesi, Lorenzo,

Ruhstaller, Thomas,

Stearns, Vered,

Láng, István,

Di Leo, Angelo,

Puglisi, Fabio,

Spazzapan, Simon,

Colleoni, Marco,

Francis, Prudence A,

Burstein, Harold J,

Gómez, Henry L,

Bonnefoi, Hervé R,

Tondini, Carlo,

Maibach, Rudolf,

Goldhirsch, Aron,

Davidson, Nancy E,

Rabaglio-Poretti, Manuela,

Regan, Meredith M,

Ingle, James N,

Bellet, Meritxell,

Goetz, Matthew P,

Martino, Silvana,

Pinotti, Graziella,

Ciruelos, Eva,

Winer, Eric P,

Gelber, Richard D,

Ruepp, Barbara,

Walley, Barbara A,

Pagani, Olivia

2018

Overview

At 8 years of follow-up, premenopausal women with breast cancer had higher rates of disease-free and overall survival with the addition of ovarian suppression to antiestrogen therapy and a higher rate of hormonal side effects than with tamoxifen alone.

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Publisher

Massachusetts Medical Society

Subject

Adjuvants

/ Adult

/ Androstadienes - adverse effects

/ Androstadienes - therapeutic use

/ Antineoplastic Agents, Hormonal - adverse effects

/ Antineoplastic Agents, Hormonal - therapeutic use

/ Aromatase