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Short-Term Inhibition of Parathyroid Hormone Secretion by a Calcium-Receptor Agonist in Patients with Primary Hyperparathyroidism
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Short-Term Inhibition of Parathyroid Hormone Secretion by a Calcium-Receptor Agonist in Patients with Primary Hyperparathyroidism
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Short-Term Inhibition of Parathyroid Hormone Secretion by a Calcium-Receptor Agonist in Patients with Primary Hyperparathyroidism
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Journal Article
Short-Term Inhibition of Parathyroid Hormone Secretion by a Calcium-Receptor Agonist in Patients with Primary Hyperparathyroidism
1997
Overview
Most patients with primary hyperparathyroidism in the United States are asymptomatic.
1
–
3
Although the usual treatment for this disorder is surgical removal of the abnormal parathyroid gland or glands, the need for surgery has been questioned because of the absence of symptoms and absence of progression of the disorder.
4
–
7
At this time, however, there are no alternatives to surgery that can reduce both serum parathyroid hormone and serum calcium concentrations in these patients. An effective medical therapy would provide an option not only for asymptomatic patients but also for those in whom parathyroid surgery is contraindicated because of intercurrent . . .
Publisher
Massachusetts Medical Society
Subject
/ Aniline Compounds - pharmacology
/ Aniline Compounds - therapeutic use
/ Biological and medical sciences
/ Calcium
/ Dose-Response Relationship, Drug
/ Female
/ Hormones
/ Humans
/ Hyperparathyroidism - drug therapy
/ Hyperparathyroidism - metabolism
/ Parathyroid Hormone - secretion
/ Pharmacology. Drug treatments
/ Women
