Asset Details
Do you wish to reserve the book?
Decreased Neutrophil Function as a Cause of Retained Placenta in Dairy Cattle
Hey, we have placed the reservation for you!
By the way, why not check out events that you can attend while you pick your title.
Oops! Something went wrong.
Looks like we were not able to place the reservation. Kindly try again later.
Are you sure you want to remove the book from the shelf?
Decreased Neutrophil Function as a Cause of Retained Placenta in Dairy Cattle
Do you wish to request the book?
Decreased Neutrophil Function as a Cause of Retained Placenta in Dairy Cattle
Please be aware that the book you have requested cannot be checked out. If you would like to checkout this book, you can reserve another copy
We have requested the book for you!
Your request is successful and it will be processed during the Library working hours. Please check the status of your request in My Requests.
Oops! Something went wrong.
Looks like we were not able to place your request. Kindly try again later.
Journal Article
Decreased Neutrophil Function as a Cause of Retained Placenta in Dairy Cattle
2002
Overview
It is unclear why some cows fail to expel the placenta following calving. One theory suggests the fetal placenta must be recognized as \"foreign\" tissue and rejected by the immune system after parturition to cause expulsion of the placenta. We hypothesized that impaired neutrophil function causes retained placenta (RP). We examined the ability of neutrophils to recognize fetal cotyledon tissue as assessed by a chemotaxis assay, which utilized a placental homogenate obtained from a spontaneously expelled placenta as the chemoattractant. Neutrophil killing ability was also estimated by determining myeloperoxidase activity in isolated neutrophils. Blood samples were obtained from 142 periparturient dairy cattle in two herds. Twenty cattle developed RP (14.1%). Neutrophils isolated from blood of cows with RP had significantly lower neutrophil function in both assays before calving, and this impaired function lasted for 1 to 2 wk after parturition. The addition of antibody directed against interleukin-8 (IL-8) to the cotyledon preparation used as a chemoattractant inhibited chemotaxis by 41%, suggesting that one of the chemoattractants present in the cotyledon at parturition is IL-8. At calving, plasma IL-8 concentration was lower in RP cows (51 +/- 12 pg/ml) than in cows expelling the placenta normally (134 +/- 11 pg/ml). From these data, we suggest that neutrophil function is a determining factor for the development of RP in dairy cattle. Also, depressed production of IL-8 may be a factor affecting neutrophil function in cows developing RP.
Publisher
Am Dairy Sci Assoc,American Dairy Science Association
Subject
/ Biological and medical sciences
/ blood
/ Cattle
/ Cattle Diseases - immunology
/ Female
/ Fundamental and applied biological sciences. Psychology
/ Mother. Fetoplacental unit. Mammary gland. Milk
/ placenta
/ Placenta Diseases - immunology
/ Placenta Diseases - veterinary
/ Placenta, Retained - immunology
/ Placenta, Retained - veterinary
