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Intensive Diabetes Therapy and Carotid Intima–Media Thickness in Type 1 Diabetes Mellitus
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Intensive Diabetes Therapy and Carotid Intima–Media Thickness in Type 1 Diabetes Mellitus
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Journal Article
Intensive Diabetes Therapy and Carotid Intima–Media Thickness in Type 1 Diabetes Mellitus
2003
Overview
Carotid intima–media thickness is considered to be a measure of atherosclerosis. This study examined intima–media thickness in participants in the Diabetes Control and Complications Trial. Six years after the trial ended, the progression of intima–media thickness was significantly less in patients who had received intensive as compared with conventional therapy.
Diabetes mellitus is accompanied by a substantial increase in the risk of cardiovascular disease.
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Most epidemiologic and clinical-trial data have derived from the study of type 2 diabetes, in which cardiovascular disease accounts for 70 percent of all deaths.
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Much less is known about cardiovascular disease in type 1 diabetes. Although the absolute risk of cardiovascular disease is lower in patients with type 1 diabetes than in those with type 2 diabetes, owing in part to their younger age, the relative risk, as compared with that of nondiabetic persons of similar age, may be increased by a factor . . .
Publisher
Massachusetts Medical Society
Subject
/ Adult
/ Arteriosclerosis - diagnostic imaging
/ Arteriosclerosis - pathology
/ Associated diseases and complications
/ Biological and medical sciences
/ Carotid Artery Diseases - diagnostic imaging
/ Carotid Artery Diseases - etiology
/ Carotid Artery Diseases - pathology
/ Carotid Artery, Common - diagnostic imaging
/ Carotid Artery, Common - pathology
/ Diabetes
/ Diabetes Mellitus, Type 1 - complications
/ Diabetes Mellitus, Type 1 - pathology
/ Diabetes Mellitus, Type 1 - therapy
/ Diabetes. Impaired glucose tolerance
/ Endocrine pancreas. Apud cells (diseases)
/ Female
/ Humans
/ Male
/ Randomized Controlled Trials as Topic
/ Therapy
/ Tunica Intima - diagnostic imaging
