Journal Article

Oat Polar Lipids Improve Cardiometabolic-Related Markers after Breakfast and a Subsequent Standardized Lunch: A Randomized Crossover Study in Healthy Young Adults

Hossain, Mohammad Mukul, Tovar, Juscelino, Petersson, Karin, Cloetens, Lieselotte, Prothon, Frederic, Florido, Maria T. Soria, Nilsson, Anne

2021

Overview

It has been suggested that intake of polar lipids may beneficially modulate various metabolic variables. The purpose of this study was to evaluate the effect of oat polar lipids on postprandial and second meal glycemic regulation, blood lipids, gastrointestinal hormones, and subjective appetite-related variables in healthy humans. In a randomized design, twenty healthy subjects ingested four liquid cereal-based test beverages (42 g of available carbohydrates) containing: i. 30 g of oat oil with a low concentration (4%) of polar lipids (PLL), ii. 30 g of oat oil containing a high concentration (40%) of polar lipids (PLH), iii. 30 g of rapeseed oil (RSO), and iv. no added lipids (NL). The products were served as breakfast meals followed by a standardized lunch. Test variables were measured at fasting and during 3 h after breakfast and two additional hours following a standardized lunch. PLH reduced glucose and insulin responses after breakfast (0–120 min) compared to RSO, and after lunch (210–330 min) compared to RSO and PLL (p < 0.05). Compared to RSO, PLH resulted in increased concentrations of the gut hormones GLP-1 and PYY after the standardized lunch (p < 0.05). The results suggest that oat polar lipids have potential nutraceutical properties by modulating acute and second meal postprandial metabolic responses.

• Publisher: MDPI AG,MDPI
• Subject: Adult / Appetite / Appetite - drug effects / Avena - chemistry / Biomarkers - blood / blood / Body mass index / breakfast / Breakfast - physiology / Cardiometabolic Risk Factors / Cross-Over Studies / Diabetes / dietary supplements / Fatty acids / Female / Gastrointestinal Hormones - blood / gastrointestinal system / glucagon-like peptide 1 / Glucose / glycemic control / Glycemic Index - drug effects / Health care / Health Sciences / Hormones / Humans / Hälsovetenskap / Insulin / Lipids / Lipids - administration & dosage / Lipids - blood / Lipids - chemistry / liquids / lunch / Lunch - physiology / Male / Meals / Medical and Health Sciences / Medicin och hälsovetenskap / Metabolism / Nutrition and Dietetics / Näringslära och dietkunskap / Oats / Peptides / Plasma / Postprandial Period - drug effects / rapeseed oil / Single-Blind Method / Triglycerides / Young adults