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Erythromycin-Resistant Group A Streptococci in Schoolchildren in Pittsburgh
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Erythromycin-Resistant Group A Streptococci in Schoolchildren in Pittsburgh
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Journal Article
Erythromycin-Resistant Group A Streptococci in Schoolchildren in Pittsburgh
2002
Overview
In a longitudinal study at an elementary school in Pittsburgh, group A streptococci with resistance to erythromycin were unexpectedly identified in surveillance throat cultures in January 2001. Through May 2001, nearly half the isolates were resistant to erythromycin, and 22 of 46 children with resistant isolates had multiple cultures that were positive for this resistant streptococcus.
At a school in Pittsburgh, nearly half the isolates were resistant.
Group A streptococci are the most frequent and important cause of bacterial pharyngitis in children and adults.
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Although many antibiotics are effective for the treatment of streptococcal pharyngitis, penicillin V remains the drug of choice.
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Erythromycin is recommended for persons who are allergic to penicillin.
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Azithromycin is not recommended as first-line therapy for pharyngitis due to group A streptococci; however, many practitioners find the five-day regimen of one dose of azithromycin per day attractive. Azithromycin and other macrolide antibiotics are also frequently prescribed for nonstreptococcal pharyngitis and other upper respiratory tract infections, and the rates of prescription . . .
Publisher
Massachusetts Medical Society
Subject
/ Anti-Bacterial Agents - pharmacology
/ Anti-Bacterial Agents - therapeutic use
/ Antibiotics. Antiinfectious agents. Antiparasitic agents
/ Biological and medical sciences
/ Child
/ Clindamycin - therapeutic use
/ Erythromycin - therapeutic use
/ Female
/ Humans
/ Male
/ Penicillins - therapeutic use
/ Pharmacology. Drug treatments
/ Streptococcal Infections - drug therapy
/ Streptococcal Infections - microbiology
/ Streptococcus pyogenes - drug effects
/ Streptococcus pyogenes - genetics
/ Streptococcus pyogenes - isolation & purification
/ Students
